The Utility of a Population Approach in Drug-Drug Interaction Assessments: A Simulation Evaluation.
This study aims at evaluating the utility of the population pharmacokinetics approach in therapeutic protein drug-drug-interaction (DDI) assessment. Simulations were conducted for 2 representative victim drugs, methotrexate and trastuzumab, using a parallel-group design with and without the interact...
| Publicado en: | Journal of Clinical Pharmacology Vol. 57; no. 10; pp. 1268 - 1279 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2017
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| Acceso en línea: | Ver este registro en EBSCOhost |