Conducting and reporting trials for older people.

Randomised controlled trials provide the most rigorous test of efficacy and effectiveness for interventions used in healthcare. They underpin much of clinical practice, yet older people are often excluded from studies, resulting in uncertainty about risks and benefits of new treatments. Encouraging...

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Publicado en:Age & Ageing Vol. 46; no. 6; pp. 889 - 895
Autores principales: WITHAM, MILES D., STOTT, DAVID J.
Formato: Artículo
Publicado: Oxford University Press / USA Nov2017
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Conducting and reporting trials for older people.
      aug:
        au:
          WITHAM, MILES D.
          STOTT, DAVID J.
        affil:
          Clinical Reader in Ageing and Health, School of Medicine, University of Dundee, Dundee DD1 9SY, UK
          Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
      su:
        Authorship
        Publishing
        Randomized controlled trials
        Old age
        Experimental design
        Manuscripts
        Research evaluation
      sug:
        subj:
          Authorship
          Publishing
          Randomized controlled trials
          Old age
          Book Publishers
          Other publishers
          All Other Publishers
          Experimental design
          Manuscripts
          Research evaluation
      keyword:
        older people
        randomised controlled trials
        Research methods
        older people
        randomised controlled trials
        Research methods
      ab: Randomised controlled trials provide the most rigorous test of efficacy and effectiveness for interventions used in healthcare. They underpin much of clinical practice, yet older people are often excluded from studies, resulting in uncertainty about risks and benefits of new treatments. Encouraging inclusion of older people in randomised controlled trials and reporting of trial results in a rigorous manner is a key function of clinical geriatrics journals such as Age and Ageing. This article provides practical advice on how to report randomised controlled trials that are targeted at older people. Some of these issues are generic, but there are specific requirements which apply to most studies of older people. Recording and reporting basic characteristics of recruits in terms of physical function, cognition, comorbidity and/or frailty is vital to allow proper interpretation of the external validity of the trial. Adverse effects should include consideration of common geriatric problems including falls. Authors should follow the CONSORT reporting guidelines (CONsolidated Standards Of Reporting Trials) to enhance the transparency and quality of their manuscript.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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