Vitamin D and mental health in children and adolescents.
While vitamin D is known to be relevant for bone health, evidence has recently accumulated for an impact on mental health. To identify the potential benefits and limitations of vitamin D for mental health, an understanding of the physiology of vitamin D, the cut-off values for vitamin D deficiency a...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 26; no. 9; pp. 1043 - 1067 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2017
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125947710&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 125947710 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Sep2017 vid: 26 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 125947710 143981460 10.1007/s00787-017-0949-3 125947710 ppf: 1043 ppct: 24 formats: fmt: @attributes: type: P tig: atl: Vitamin D and mental health in children and adolescents. aug: au: Föcker, Manuel Antel, Jochen Ring, Stefanie Hahn, Denise Kanal, Özlem Öztürk, Dana Hebebrand, Johannes Libuda, Lars affil: Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Wickenburgstr. 21, 45147 Essen, Germany sug: ab: While vitamin D is known to be relevant for bone health, evidence has recently accumulated for an impact on mental health. To identify the potential benefits and limitations of vitamin D for mental health, an understanding of the physiology of vitamin D, the cut-off values for vitamin D deficiency and the current status of therapeutic trials is paramount. Results of a systematic PUBMED search highlight the association of vitamin D levels and mental health conditions. Here, we focus on children and adolescents studies as well as randomized controlled trials on depression in adults. 41 child and adolescent studies were identified including only 1 randomized controlled and 7 non-controlled supplementation trials. Overall, results from 25 cross-sectional studies as well as from 8 longitudinal studies suggest a role of vitamin D in the pathogenesis of mental disorders in childhood and adolescence. Findings from supplementation trials seem to support this hypothesis. However, randomized controlled trials in adults revealed conflicting results. Randomized controlled trials in childhood and adolescents are urgently needed to support the potential of vitamin D as a complementary therapeutic option in mental disorders. Study designs should consider methodological challenges, e.g., hypovitaminosis D at baseline, appropriate supplementation doses, sufficient intervention periods, an adequate power, clinically validated diagnostic instruments, and homogenous, well-defined risk groups. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|