A New Evolutionary Algorithm-Based Home Monitoring Device for Parkinson's Dyskinesia.
Parkinson's disease (PD) is a neurodegenerative movement disorder. Although there is no cure, symptomatic treatments are available and can significantly improve quality of life. The motor, or movement, features of PD are caused by reduced production of the neurotransmitter dopamine. Dopamine deficie...
| Publicado en: | Journal of Medical Systems Vol. 41; no. 11; pp. 1 - 9 |
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| Autores principales: | , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Nov2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125950751&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 125950751 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01485598 4N0 jtl: Journal of Medical Systems issn: 01485598 maglogo: N pubinfo: dt: Nov2017 vid: 41 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 125950751 125950751 125950751 10.1007/s10916-017-0811-7 125950751 ppf: 1 ppct: 8 formats: fmt: @attributes: type: P tig: atl: A New Evolutionary Algorithm-Based Home Monitoring Device for Parkinson's Dyskinesia. aug: au: Lones, Michael Alty, Jane Cosgrove, Jeremy Duggan-Carter, Philippa Jamieson, Stuart Naylor, Rebecca Turner, Andrew Smith, Stephen affil: School of Mathematical and Computer Sciences , Heriot-Watt University , Edinburgh UK sug: subj: Parkinson Disease Dyskinesias Algorithms Human Monitoring, Physiologic Home Health Care Dopamine Quality of Life ab: Parkinson's disease (PD) is a neurodegenerative movement disorder. Although there is no cure, symptomatic treatments are available and can significantly improve quality of life. The motor, or movement, features of PD are caused by reduced production of the neurotransmitter dopamine. Dopamine deficiency is most often treated using dopamine replacement therapy. However, this therapy can itself lead to further motor abnormalities referred to as dyskinesia. Dyskinesia consists of involuntary jerking movements and muscle spasms, which can often be violent. To minimise dyskinesia, it is necessary to accurately titrate the amount of medication given and monitor a patient's movements. In this paper, we describe a new home monitoring device that allows dyskinesia to be measured as a patient goes about their daily activities, providing information that can assist clinicians when making changes to medication regimens. The device uses a predictive model of dyskinesia that was trained by an evolutionary algorithm, and achieves AUC>0.9 when discriminating clinically significant dyskinesia. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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