Can Diet Modulate Helicobacter pylori-associated Gastric Pathogenesis? An Evidence-Based Analysis.

Helicobacter pylori is involved in the pathogenesis of gastritis, peptic ulcer, and gastric cancer. The infection is prevalent in more than half of the world's population. Although the infection may lead to detrimental consequences, still the majority of the infected individuals only develop mild ga...

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Publicado en:Nutrition & Cancer Vol. 69; no. 7; pp. 979 - 990
Autores principales: Zaidi, Syed Faisal, Ahmed, Kanwal, Saeed, Sheikh Abdul, Khan, Usmanghani, Sugiyama, Toshiro
Formato: review tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/01635581.2017.1359310
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        atl: Can Diet Modulate Helicobacter pylori-associated Gastric Pathogenesis? An Evidence-Based Analysis.
      aug:
        au:
          Zaidi, Syed Faisal
          Ahmed, Kanwal
          Saeed, Sheikh Abdul
          Khan, Usmanghani
          Sugiyama, Toshiro
        affil: Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah, Kingdom of Saudi Arabia
      sug:
        subj:
          Diet
          Helicobacter Infections Physiopathology
          Helicobacter Infections Complications
          Gastritis Risk Factors
          Peptic Ulcer Risk Factors
          Stomach Neoplasms Risk Factors
          Helicobacter Infections Epidemiology
          Life Style
      ab: Helicobacter pylori is involved in the pathogenesis of gastritis, peptic ulcer, and gastric cancer. The infection is prevalent in more than half of the world's population. Although the infection may lead to detrimental consequences, still the majority of the infected individuals only develop mild gastritis. Several factors are behind this paradoxical outcome including virulence of the infecting H. pylori strains, genetic background of the host, and factors related to lifestyle such as dietary habits. Among these, lifestyle including dietary factors was not in the limelight, until recently, as one of the important factors that could modulate H. pylori-linked gastric diseases. This review is directed to gather and elucidate the role of dietary components in augmenting or attenuating pathological processes initiated by H. pylori. Available evidence strongly supports the notion that the diet may play a critical role in defining the final outcome of H. pylori infection particularly if certain dietary components are taken on a regular basis for a long time. Despite a recent surge in research related to the role of dietary ingredients, further studies involving large-scale clinical trials are required to gain a better understanding of the precise role played by the dietary ingredients in H. pyloriassociated pathogenesis.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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