Local Application of Platelet-Rich Fibrin During Lower Third Molar Extraction Improves Treatment Outcomes.
Purpose: Application of platelet-rich fibrin (PRF) during tooth extraction is able to accelerate wound healing, stimulate osseous and soft tissue regeneration, and reduce unwanted side effects. The aim of this meta-analysis was to investigate the effect of local application of PRF on controlling pos...
| Publicado en: | Journal of Oral & Maxillofacial Surgery (02782391) Vol. 75; no. 12; pp. 2497 - 2507 |
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| Autores principales: | , , , , |
| Formato: | review Journal Article |
| Publicado: |
W B Saunders
Dec2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126162245&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 126162245 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02782391 1YP jtl: Journal of Oral & Maxillofacial Surgery (02782391) issn: 02782391 maglogo: N pubinfo: dt: Dec2017 vid: 75 iid: 12 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 126162245 126162245 NLM28672135 126162245 10.1016/j.joms.2017.05.034 NLM28672135 126162245 ppf: 2497 ppct: 10 formats: tig: atl: Local Application of Platelet-Rich Fibrin During Lower Third Molar Extraction Improves Treatment Outcomes. aug: au: He, Yun Chen, Junliang Huang, Yue Pan, Qin Nie, Minhai affil: Associate Professor, Orofacial Reconstruction and Regeneration Laboratory, Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Southwest Medical University, Luzhou, China sug: ab: Purpose: Application of platelet-rich fibrin (PRF) during tooth extraction is able to accelerate wound healing, stimulate osseous and soft tissue regeneration, and reduce unwanted side effects. The aim of this meta-analysis was to investigate the effect of local application of PRF on controlling postoperative signs and symptoms after the extraction of an impacted lower third molar.Materials and Methods: A systematic search of PubMed, Web of Science, Embase, and the Cochrane Library was performed to identify all studies published up to October 2016 that investigated the effect of PRF on lower third molar extraction. Pain, swelling, trismus, alveolar osteitis (AO), and osteoblastic activity were extracted to evaluate the effect of PRF. After quality assessment, meta-analysis was performed with RevMan software (version 5.3; Cochrane Library Software, Oxford, UK).Results: After the search and selection process, 10 studies were selected in this meta-analysis, including 468 cases of PRF application and 467 cases of non-PRF application. Of the studies, 9 were randomized controlled trials, including 7 split-mouth studies, and there was 1 retrospective case-control study. The results indicated that PRF significantly relieves pain (P = .01) and 3-day postoperative swelling (P = .03) and reduces the incidence of AO (P < .0001). However, there were no significant differences between the PRF and non-PRF groups with respect to 1-day postoperative swelling and osteoblastic activity.Conclusions: Local application of PRF after lower third molar extraction is a valid method for relieving pain and 3-day postoperative swelling and reducing the incidence of AO. For patients undergoing complicated surgical extraction, PRF might be a recommendation for local application into the sockets. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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