Accuracy Validation of an Automated Method for Prostate Segmentation in Magnetic Resonance Imaging.

Three dimensional (3D) manual segmentation of the prostate on magnetic resonance imaging (MRI) is a laborious and time-consuming task that is subject to inter-observer variability. In this study, we developed a fully automatic segmentation algorithm for T2-weighted endorectal prostate MRI and evalua...

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Published in:Journal of Digital Imaging Vol. 30; no. 6; pp. 782 - 796
Main Authors: Shahedi, Maysam, Cool, Derek, Bauman, Glenn, Bastian-Jordan, Matthew, Fenster, Aaron, Ward, Aaron
Format: diagnostic images equations & formulas tables/charts Journal Article
Published: Springer Nature Dec2017
Online Access:View this record in EBSCOhost
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      dt: Dec2017
      vid: 30
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-017-9964-7
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        atl: Accuracy Validation of an Automated Method for Prostate Segmentation in Magnetic Resonance Imaging.
      aug:
        au:
          Shahedi, Maysam
          Cool, Derek
          Bauman, Glenn
          Bastian-Jordan, Matthew
          Fenster, Aaron
          Ward, Aaron
        affil: The Department of Medical Imaging , The University of Western Ontario , London Canada
      sug:
        subj:
          Prostatic Neoplasms
          Digital Imaging
          Magnetic Resonance Imaging
          Image Enhancement Methods
          Matched-Pair Analysis
          Prostate
          Image Processing, Computer Assisted Methods
          Algorithms
          Validity Evaluation
      ab: Three dimensional (3D) manual segmentation of the prostate on magnetic resonance imaging (MRI) is a laborious and time-consuming task that is subject to inter-observer variability. In this study, we developed a fully automatic segmentation algorithm for T2-weighted endorectal prostate MRI and evaluated its accuracy within different regions of interest using a set of complementary error metrics. Our dataset contained 42 T2-weighted endorectal MRI from prostate cancer patients. The prostate was manually segmented by one observer on all of the images and by two other observers on a subset of 10 images. The algorithm first coarsely localizes the prostate in the image using a template matching technique. Then, it defines the prostate surface using learned shape and appearance information from a set of training images. To evaluate the algorithm, we assessed the error metric values in the context of measured inter-observer variability and compared performance to that of our previously published semi-automatic approach. The automatic algorithm needed an average execution time of ∼60 s to segment the prostate in 3D. When compared to a single-observer reference standard, the automatic algorithm has an average mean absolute distance of 2.8 mm, Dice similarity coefficient of 82%, recall of 82%, precision of 84%, and volume difference of 0.5 cm in the mid-gland. Concordant with other studies, accuracy was highest in the mid-gland and lower in the apex and base. Loss of accuracy with respect to the semi-automatic algorithm was less than the measured inter-observer variability in manual segmentation for the same task.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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