Background parenchymal enhancement: is it just an innocent effect of estrogen on the breast?

Purpose: We aimed to retrospectively analyze whether background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) correlates with menarche, menopause, reproductive period, menstrual cycle, gravidity-parity, family history of breast cancer, and the Breast Imaging-Reporting and...

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Publicado en:Diagnostic & Interventional Radiology Vol. 23; no. 6; pp. 414 - 420
Autores principales: Arslan, Gözde, Çelik, Levent, Çubuk, Rahmi, Atasoy, Mehmet Mahir
Formato: research tables/charts Journal Article
Publicado: Galenos Yayinevi Tic. LTD. STI Nov/Dec2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov/Dec2017
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      pub: Galenos Yayinevi Tic. LTD. STI
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        10.5152/dir.2017.17048
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        atl: Background parenchymal enhancement: is it just an innocent effect of estrogen on the breast?
      aug:
        au:
          Arslan, Gözde
          Çelik, Levent
          Çubuk, Rahmi
          Atasoy, Mehmet Mahir
        affil: Department of Radiology, Maltepe University School of Medicine, İstanbul, Turkey
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Estrogens
          Image Enhancement Methods
          Breast
          Contrast Media
          Female
          Young Adult
          Retrospective Design
          Middle Age
          Aged
          Adult
          Barthel Index
          Human
          Middle Aged: 45-64 years
          Aged: 65+ years
          Adult: 19-44 years
          Female
      ab: Purpose: We aimed to retrospectively analyze whether background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) correlates with menarche, menopause, reproductive period, menstrual cycle, gravidity-parity, family history of breast cancer, and the Breast Imaging-Reporting and Data System (BI-RADS) category of the patient.Methods: The study included 126 pre- and 78 postmenopausal women who underwent breast MRI in our institute between 2011 and 2016. Patients had filled a questionnaire form before the MRI. Two radiologists blinded to patient history graded the BPEs and the results were compared and analyzed.Results: The BPE was correlated with patient age and the day of menstrual cycle (P < 0.01 for both). No correlation was found with menarche age, menopause age, total number of reproductive years, and family history of breast cancer. In the moderate BPE group, only 1 out of 35 patients and in the marked BPE group only 1 out of 13 patients were postmenopausal and had BI-RADS scores of 4 and 5, respectively.Conclusion: Increased symmetrical BPE is mainly due to current hormonal status in the premenopausal women. High-grade BPE, whether symmetrical or not, is rarely seen in postmenopausal women; hence, these patients should be further investigated or closely followed up.
      pubtype: Academic Journal
      doctype:
        research
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      ougenre: Article
    language: English
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