NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.

Background: In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simul...

Descripción completa

Detalles Bibliográficos
Publicado en:BioMedical Engineering OnLine Vol. 16; pp. 1 - 18
Autores principales: Bo Zhang, Ji Dai, Tao Zhang, Zhang, Bo, Dai, Ji, Zhang, Tao
Formato: pictorial tables/charts Journal Article
Publicado: BioMed Central 11/13/2017
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126239748&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 126239748
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        1475925X
        1CGX
      jtl: BioMedical Engineering OnLine
      issn: 1475925X
      maglogo: N
    pubinfo:
      dt: 11/13/2017
      vid: 16
      pid: 24147
      pub: BioMed Central
    artinfo:
      ui:
        126239748
        126239748
        NLM29132360
        126239748
        10.1186/s12938-017-0419-7
        NLM29132360
        126239748
      ppf: 1
      ppct: 17
      formats:
      tig:
        atl: NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.
      aug:
        au:
          Bo Zhang
          Ji Dai
          Tao Zhang
          Zhang, Bo
          Dai, Ji
          Zhang, Tao
        affil: State Key Laboratory of Brain and Cognitive Sciences, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
      sug:
        subj:
          Software
          Signal Processing, Computer Assisted
          Electrophysiology
          Saccades Physiology
          Algorithms
          User-Computer Interface
          Funding Source
      ab: Background: In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions. Additionally, these toolboxes require that the input data be in a specific format, which can be inconvenient to users. Therefore, the development of a highly integrated toolbox that can process multiple types of data regardless of input data format and perform basic analysis for general electrophysiological experiments is incredibly useful.Results: Here, we report the development of a Python based open-source toolbox, referred to as NeoAnalysis, to be used for quick electrophysiological data processing and analysis. The toolbox can import data from different data acquisition systems regardless of their formats and automatically combine different types of data into a single file with a standardized format. In cases where additional spike sorting is needed, NeoAnalysis provides a module to perform efficient offline sorting with a user-friendly interface. Then, NeoAnalysis can perform regular analog signal processing, spike train, and local field potentials analysis, behavioral response (e.g. saccade) detection and extraction, with several options available for data plotting and statistics. Particularly, it can automatically generate sorted results without requiring users to manually sort data beforehand. In addition, NeoAnalysis can organize all of the relevant data into an informative table on a trial-by-trial basis for data visualization. Finally, NeoAnalysis supports analysis at the population level.Conclusions: With the multitude of general-purpose functions provided by NeoAnalysis, users can easily obtain publication-quality figures without writing complex codes. NeoAnalysis is a powerful and valuable toolbox for users doing electrophysiological experiments.
      pubtype: Academic Journal
      doctype:
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N