Comparative Transcriptome Analysis Reveals Related Regulatory Mechanisms of Androgenic Gland in Eriocheir sinensis.

Chinese mitten crab (Eriocheir sinensis) is one of the most commercially important aquaculture species in China. The androgenic gland (AG) of crustaceans plays pivotal roles in the regulation of male differentiation and in maintaining the male sexual characteristics. In order to reveal related mecha...

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 13
Autores principales: Fu, Chunpeng, Zeng, Qifan, Li, Fajun, Wang, Huicui, Sun, Jian, Wang, Hui
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 11/9/2017
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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      dt: 11/9/2017
      vid: 2017
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        126267284
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        10.1155/2017/4956216
        126267284
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        atl: Comparative Transcriptome Analysis Reveals Related Regulatory Mechanisms of Androgenic Gland in Eriocheir sinensis.
      aug:
        au:
          Fu, Chunpeng
          Zeng, Qifan
          Li, Fajun
          Wang, Huicui
          Sun, Jian
          Wang, Hui
        affil: College of Animal Science and Technology, Shandong Agricultural University, Tai’an 271018, China
      sug:
        subj:
          Testis Physiology
          Gene Expression Profiling
          Androgens
          Animal Studies
          Crustacea China
          Secretions
          Cell Proliferation
          Gene Expression
          Metabolic Networks and Pathways
          Signal Transduction
          Receptors, Cell Surface
          Reproduction
          Cell Differentiation
          Somatomedins
          Transcription Factors
          Sexuality
          China
      ab: Chinese mitten crab (Eriocheir sinensis) is one of the most commercially important aquaculture species in China. The androgenic gland (AG) of crustaceans plays pivotal roles in the regulation of male differentiation and in maintaining the male sexual characteristics. In order to reveal related mechanisms in AG, we compared transcriptomes of AG between proliferation and secretion phase. A total of 72,000 unigenes and 4,027 differentially expressed genes were obtained. Gene ontology enrichment analysis indicated that biological processes and metabolic pathways related to protein synthesis and secretion such as transcription, translation, and signal transduction were significantly enriched. Critical genes such as IAG, SXL, TRA-2, SRY, FTZ-F1, FOXL2, and FEM-1 were identified and potentially involved in maintaining the testis development and spermatogenesis. Ribosomes pathway revealed the cause of insulin-like androgenic gland hormone secretion increase. Three insulin-like receptors were thought to be associated with growth and spermatogenesis. In the neuroactive ligand-receptor interaction pathway, the expression of octopamine receptor, 5-HT receptor 1, and melatonin receptor was significantly changed, which revealed the key regulation mechanism of aggressive and mating behavior of males. Comparative transcriptome analysis provided new insights into the genome-wide molecular mechanisms of AG development and the regulatory mechanisms of male development.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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