Pyoderma Gangrenosum: A Critical Appraisal.

Pyoderma gangrenosum (PG) is an uncommon cutaneous disease, presenting with recurrent painful ulcerations most commonly on the lower extremities. The diagnosis is made according to a typical presentation, skin lesion morphology, skin biopsy, histopathology, and the exclusion of other etiologies. Cla...

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Publicado en:Advances in Skin & Wound Care Vol. 30; no. 12; pp. 534 - 543
Autores principales: Shavit, Eran, Alavi, Afsaneh, Sibbald, R. Gary
Formato: Journal Article
Publicado: Lippincott Williams & Wilkins Dec2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2017
      vid: 30
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Pyoderma Gangrenosum: A Critical Appraisal.
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        au:
          Shavit, Eran
          Alavi, Afsaneh
          Sibbald, R. Gary
        affil: Dermatologist, Clinical Fellow, Division of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada
      sug:
        subj:
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Drug Therapy
          Education, Continuing (Credit)
          Lower Extremity
          Skin Diseases Etiology
          Biopsy
          Diagnosis, Differential
          Pain Etiology
          Antiinflammatory Agents Administration and Dosage
          Immunosuppressive Agents Administration and Dosage
          Wound Care
          Antiinfective Agents Administration and Dosage
          Pyoderma Gangrenosum Complications
          Infection Etiology
          Infection Drug Therapy
          Pyoderma Gangrenosum Physiopathology
          Pyoderma Gangrenosum Classification
          Algorithms
      ab: Pyoderma gangrenosum (PG) is an uncommon cutaneous disease, presenting with recurrent painful ulcerations most commonly on the lower extremities. The diagnosis is made according to a typical presentation, skin lesion morphology, skin biopsy, histopathology, and the exclusion of other etiologies. Classically, PG presents with painful ulcers with well-defined violaceous borders; other variants including bullous, pustular, and vegetative/granulomatous can also occur. Treatment of PG involves a combination of topical and systemic anti-inflammatory and immunosuppressive medications, wound care, antimicrobial agents for secondary infections, and treatment of the underlying etiology. This article is a continuing education review of the literature with a focus on the clinical application of the pathophysiology, diagnosis, and treatment of this challenging disease.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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