Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF- α.

Bmal1, a clock gene, is associated with depression, hypertrophy, metabolic syndrome and diabetes. Smad3, which is involved in the TGF-β signaling pathway, plays an important role in the regulation of tumor progression, fibrosis, obesity and diabetes. Our previous report showed that Smad3 has circadi...

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Bibliographic Details

Published in:	Histochemistry & Cell Biology Vol. 148; no. 6; pp. 617 - 625
Main Authors:	Sato, Fuyuki, Kohsaka, Akira, Takahashi, Kana, Otao, Saki, Kitada, Yusuke, Iwasaki, Yoshiyuki, Muragaki, Yasuteru
Format:	Journal Article
Published:	Springer Nature Dec2017
Online Access:	View this record in EBSCOhost