Image Restoration for Fluorescence Planar Imaging with Diffusion Model.

Fluorescence planar imaging (FPI) is failure to capture high resolution images of deep fluorochromes due to photon diffusion. This paper presents an image restoration method to deal with this kind of blurring. The scheme of this method is conceived based on a reconstruction method in fluorescence mo...

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 19
Autores principales: Zhang, Xuanxuan, Gong, Yuzhu, Li, Yang, Cao, Xu, Zhu, Shouping
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 11/27/2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 11/27/2017
      vid: 2017
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2017/2010512
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        atl: Image Restoration for Fluorescence Planar Imaging with Diffusion Model.
      aug:
        au:
          Zhang, Xuanxuan
          Gong, Yuzhu
          Li, Yang
          Cao, Xu
          Zhu, Shouping
        affil: Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education & School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710071, China
      sug:
        subj:
          Diagnostic Imaging Methods
          Tomography, Optical Utilization
          Mathematics
          Image Processing, Computer Assisted
      ab: Fluorescence planar imaging (FPI) is failure to capture high resolution images of deep fluorochromes due to photon diffusion. This paper presents an image restoration method to deal with this kind of blurring. The scheme of this method is conceived based on a reconstruction method in fluorescence molecular tomography (FMT) with diffusion model. A new unknown parameter is defined through introducing the first mean value theorem for definite integrals. System matrix converting this unknown parameter to the blurry image is constructed with the elements of depth conversion matrices related to a chosen plane named focal plane. Results of phantom and mouse experiments show that the proposed method is capable of reducing the blurring of FPI image caused by photon diffusion when the depth of focal plane is chosen within a proper interval around the true depth of fluorochrome. This method will be helpful to the estimation of the size of deep fluorochrome.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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