Diaphragmatic Thickness Fraction in Subjects at High-Risk for COPD Exacerbations.

BACKGROUND: Ultrasound-based diaphragmatic thickness fraction is a reflection of the size and function of the diaphragm. This study aimed to examine the value of this measurement in identifying patients with COPD who are at high risk for the development of symptoms and exacerbations. METHODS: This c...

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Publicado en:Respiratory Care Vol. 62; no. 12; pp. 1565 - 1571
Autores principales: Eryü ksel, Emel, Cimşit, Canan, Bekir, Melahat, Cimsit, Çagatay, Karakurt, Sait
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Dec2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2017
      vid: 62
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        10.4187/respcare.05646
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        atl: Diaphragmatic Thickness Fraction in Subjects at High-Risk for COPD Exacerbations.
      aug:
        au:
          Eryü ksel, Emel
          Cimşit, Canan
          Bekir, Melahat
          Cimsit, Çagatay
          Karakurt, Sait
        affil: Department of Pulmonary and Critical Care, School of Medicine, Marmara University, Istanbul, Turkey
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive
          Disease Exacerbation Risk Factors
          Human
          Cross Sectional Studies
          Turkiye
          Plethysmography
          Male
          Female
          Middle Age
          Aged
          Reliability and Validity
          Descriptive Statistics
          Data Analysis Software
          Kruskal-Wallis Test
          Spearman's Rank Correlation Coefficient
          Mann-Whitney U Test
          Scales
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: BACKGROUND: Ultrasound-based diaphragmatic thickness fraction is a reflection of the size and function of the diaphragm. This study aimed to examine the value of this measurement in identifying patients with COPD who are at high risk for the development of symptoms and exacerbations. METHODS: This cross-sectional study included 53 subjects with COPD. Respiratory function test results, ultrasonography-based diaphragmatic thickness, symptom scores (modified Medical Research Council dyspnea scale); COPD Assessment Test results, and number of previous exacerbations and admissions were recorded. RESULTS: Only age showed an inverse and weak relation with percent thickness fraction (r = -0.37, P = .006). None of the other variables tested correlated significantly with percent thickness fraction. No association was found between percent thickness fraction and exacerbation frequency, modified Medical Research Council dyspnea scale and COPD Assessment Test symptom scores, or Global Initiative for Chronic Obstructive Lung Disease ABCD risk/symptom assessments. CONCLUSIONS: Diaphragmatic thickness fraction measurements based on diaphragmatic ultrasound assessment in subjects with COPD seemed to be unable to identify subjects at high risk of symptoms and exacerbations as defined by the Global Initiative for Chronic Obstructive Lung Disease ABCD composite disease index.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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