The topological organization of white matter network in internet gaming disorder individuals.
White matter (WM) integrity abnormalities had been reported in Internet gaming disorder (IGD). Diffusion tensor imaging (DTI) tractography allows identification of WM tracts, potentially providing information about the integrity and organization of relevant underlying WM fiber tracts' architectures,...
| Publicado en: | Brain Imaging & Behavior Vol. 11; no. 6; pp. 1769 - 1779 |
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| Autores principales: | , , , , , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126486086&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 126486086 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Dec2017 vid: 11 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 126486086 126486086 144004448 NLM27815774 126486086 10.1007/s11682-016-9652-0 NLM27815774 126486086 ppf: 1769 ppct: 10 formats: fmt: @attributes: type: P tig: atl: The topological organization of white matter network in internet gaming disorder individuals. aug: au: Zhai, Jinquan Luo, Lin Qiu, Lijun Kang, Yongqiang Liu, Bo Yu, Dahua Lu, Xiaoqi Yuan, Kai affil: Department of Medical Imaging, The First Affiliated Hospital of Baotou Medical College , Inner Mongolia University of Science and Technology , Baotou 014010 People's Republic of China sug: subj: Brain Video Games Internet Behavior, Addictive Neural Pathways Behavior, Addictive Pathology Young Adult Male Adolescence Magnetic Resonance Imaging Cross Sectional Studies Female Brain Pathology Neural Pathways Pathology Human Questionnaires Adolescent: 13-18 years Male Female ab: White matter (WM) integrity abnormalities had been reported in Internet gaming disorder (IGD). Diffusion tensor imaging (DTI) tractography allows identification of WM tracts, potentially providing information about the integrity and organization of relevant underlying WM fiber tracts' architectures, which has been used to investigate the connectivity of cortical and subcortical structures in several brain disorders. Unfortunately, relatively little is known about the thoroughly circuit-level characterization of topological property changes of WM network with IGD. Sixteen right-hand adolescents with IGD participated in our study, according to the diagnostic criteria of IGD in DSM-5. Meanwhile, 16 age and gender-matched healthy controls were also enrolled. DTI tractography was employed to generate brain WM networks in IGD individuals and healthy controls. The 90 cortical and subcortical regions derived from AAL template were chosen as the nodes. The network parameters (i.e., Network strength, clustering coefficient, shortest path length, global efficiency, local efficiency, regional efficiency) were calculated and then correlated with the Internet addiction test (IAT) scores in IGD. IGD group showed decreased global efficiency, local efficiency and increased shortest path length. Further analysis revealed the reduced nodal efficiency in frontal cortex, anterior cingulate cortex and pallidium in IGD. In addition, the global efficiency of WM network was correlated with the IAT scores in IGD (r = -0.5927; p = 0.0155). We reported the abnormal topological organization of WM network in IGD and the association with the severity of IGD, which may provide new insights into the neural mechanism of IGD from WM network level. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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