Brain network connectivity in women exposed to intimate partner violence: a graph theory analysis study.

Evidence suggests that women who suffer from intimate partner violence (IPV) and posttraumatic stress disorder (PTSD) have structural and functional alterations in specific brain regions. Yet, little is known about how brain connectivity may be altered in individuals with IPV, but without PTSD. Wome...

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Publicado en:Brain Imaging & Behavior Vol. 11; no. 6; pp. 1629 - 1640
Autores principales: Roos, Annerine, Fouche, Jean-Paul, Stein, Dan, Stein, Dan J
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Brain network connectivity in women exposed to intimate partner violence: a graph theory analysis study.
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          Roos, Annerine
          Fouche, Jean-Paul
          Stein, Dan
          Stein, Dan J
        affil: SU/UCT MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry , Stellenbosch University , Cape Town 8000 South Africa
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          Brain
          Brain Pathology
          Young Adult
          Body Weights and Measures
          Adult
          Neural Pathways
          Neural Pathways Pathology
          Image Processing, Computer Assisted
          Adolescence
          Female
          Magnetic Resonance Imaging
          Human
          Adult: 19-44 years
          Adolescent: 13-18 years
          Female
      ab: Evidence suggests that women who suffer from intimate partner violence (IPV) and posttraumatic stress disorder (PTSD) have structural and functional alterations in specific brain regions. Yet, little is known about how brain connectivity may be altered in individuals with IPV, but without PTSD. Women exposed to IPV (n = 18) and healthy controls (n = 18) underwent structural brain imaging using a Siemens 3T MRI. Global and regional brain network connectivity measures were determined, using graph theory analyses. Structural covariance networks were created using volumetric and cortical thickness data after controlling for intracranial volume, age and alcohol use. Nonparametric permutation tests were used to investigate group differences. Findings revealed altered connectivity on a global and regional level in the IPV group of regions involved in cognitive-emotional control, with principal involvement of the caudal anterior cingulate, the middle temporal gyrus, left amygdala and ventral diencephalon that includes the thalamus. To our knowledge, this is the first evidence showing different brain network connectivity in global and regional networks in women exposed to IPV, and without PTSD. Altered cognitive-emotional control in IPV may underlie adaptive neural mechanisms in environments characterized by potentially dangerous cues.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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