Fat Quantification in the Abdomen.
Fatty liver disease is characterized histologically by hepatic steatosis, the abnormal accumulation of lipid in hepatocytes. It is classified into alcoholic fatty liver disease and nonalcoholic fatty liver disease, and is an increasingly important cause of chronic liver disease and cirrhosis. Assess...
| Publicado en: | Topics in Magnetic Resonance Imaging Vol. 26; no. 6; pp. 221 - 228 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Dec2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126526067&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 126526067 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08993459 N2D jtl: Topics in Magnetic Resonance Imaging issn: 08993459 maglogo: N pubinfo: dt: Dec2017 vid: 26 iid: 6 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 126526067 126526067 NLM29176468 126526067 10.1097/RMR.0000000000000141 NLM29176468 126526067 ppf: 221 ppct: 7 formats: tig: atl: Fat Quantification in the Abdomen. aug: au: Cheng William Hong Dehkordy, Soudabeh Fazeli Hooker, Jonathan C. Hamilton, Gavin Sirlin, Claude B. Hong, Cheng William Fazeli Dehkordy, Soudabeh affil: Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA sug: subj: Fatty Liver Magnetic Resonance Imaging Methods Adipose Tissue Abdomen Fatty Liver Metabolism Reproducibility of Results Abdomen Pathology Human Tomography, X-Ray Computed Methods Fatty Liver Pathology Scales ab: Fatty liver disease is characterized histologically by hepatic steatosis, the abnormal accumulation of lipid in hepatocytes. It is classified into alcoholic fatty liver disease and nonalcoholic fatty liver disease, and is an increasingly important cause of chronic liver disease and cirrhosis. Assessing the severity of hepatic steatosis in these conditions is important for diagnostic and prognostic purposes, as hepatic steatosis is potentially reversible if diagnosed early. The criterion standard for assessing hepatic steatosis is liver biopsy, which is limited by sampling error, its invasive nature, and associated morbidity. As such, noninvasive imaging-based methods of assessing hepatic steatosis are needed. Ultrasound and computed tomography are able to suggest the presence of hepatic steatosis based on imaging features, but are unable to accurately quantify hepatic fat content. Since Dixon's seminal work in 1984, magnetic resonance imaging has been used to compute the signal fat fraction from chemical shift-encoded imaging, commonly implemented as out-of-phase and in-phase imaging. However, signal fat fraction is confounded by several factors that limit its accuracy and reproducibility. Recently, advanced chemical shift-encoded magnetic resonance imaging methods have been developed that address these confounders and are able to measure the proton density fat fraction, a standardized, accurate, and reproducible biomarker of fat content. The use of these methods in the liver, as well as in other abdominal organs such as the pancreas, adrenal glands, and adipose tissue will be discussed in this review. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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