Tracking the Origin and Deciphering the Phylogenetic Relationship of Porcine Epidemic Diarrhea Virus in Ecuador.

In 2010, new Chinese strains of porcine epidemic diarrhea virus (PEDV), clinically more severe than the classical strains, emerged. These strains were spread to United States in 2013 through an intercontinental transmission from China with further spreading across the world, evidencing the emergent...

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 8
Autores principales: Barrera, Maritza, Garrido-Haro, Ana, Vaca, María S., Granda, Danilo, Acosta-Batallas, Alfredo, Pérez, Lester J.
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 12/12/2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 12/12/2017
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      pub: Wiley-Blackwell
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        10.1155/2017/2978718
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        atl: Tracking the Origin and Deciphering the Phylogenetic Relationship of Porcine Epidemic Diarrhea Virus in Ecuador.
      aug:
        au:
          Barrera, Maritza
          Garrido-Haro, Ana
          Vaca, María S.
          Granda, Danilo
          Acosta-Batallas, Alfredo
          Pérez, Lester J.
        affil: Facultad de Ciencias Veterinarias, Universidad Tëcnica de Manabí, Ave Urbina y Che Guevara, Portoviejo, Manabí, Ecuador
      sug:
        subj:
          Phylogenetics
          Disease Outbreaks
          Diarrhea Etiology
          Virus Diseases
          Animal Studies
          Swine
          Ecuador
          Geographic Locations
          Disease Transmission Evaluation
          United States
          Genes
          Sequence Analysis
          Epidemiology
          Microbiology
      ab: In 2010, new Chinese strains of porcine epidemic diarrhea virus (PEDV), clinically more severe than the classical strains, emerged. These strains were spread to United States in 2013 through an intercontinental transmission from China with further spreading across the world, evidencing the emergent nature of these strains. In the present study, an analysis of PEDV field sequences from Ecuador was conducted by comparing all the PEDV S gene sequences available in the GenBank database. Phylogenetic comparisons and Bayesian phylogeographic inference based on complete S gene sequences were also conducted to track the origin and putative route of PEDV. The sequence from the PED-outbreak in Ecuador was grouped into the clade II of PEDV genogroup 2a together with other sequences of isolates from Mexico, Canada, and United States. The phylogeographic study revealed the emergence of the Chinese PEDV strains, followed by spreading to US in 2013, from US to Korea, and later the introduction of PEDV to Canada, Mexico, and Ecuador directly from the US. The sources of imports of live swine in Ecuador in 2014 were mainly from Chile and US. Thus, this movement of pigs is suggested as the main way for introducing PEDV to Ecuador.
      pubtype: Academic Journal
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    language: English
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