Word Processing in Children With Autism Spectrum Disorders: Evidence From Event-Related Potentials.

Purpose: This investigation was conducted to determine whether young children with autism spectrum disorders exhibited a canonical neural response to word stimuli and whether putative event-related potential (ERP) measures of word processing were correlated with a concurrent measure of receptive lan...

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Published in:Journal of Speech, Language & Hearing Research Vol. 60; no. 12; pp. 3441 - 3456
Main Authors: Sandbank, Micheal, Yoder, Paul, Key, Alexandra P.
Format: Article
Published: American Speech-Language-Hearing Association Dec2017
Subjects:
Online Access:View this record in EBSCOhost
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      dt: Dec2017
      vid: 60
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      pub: American Speech-Language-Hearing Association
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        10.1044/2017_JSLHR-S-17-0011
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        atl: Word Processing in Children With Autism Spectrum Disorders: Evidence From Event-Related Potentials.
      aug:
        au:
          Sandbank, Micheal
          Yoder, Paul
          Key, Alexandra P.
        affil:
          Department of Special Education, University of Texas at Austin
          Special Education Department, Vanderbilt University, Nashville, TN
          Vanderbilt Kennedy Center for Research on Human Developmentand Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN
      su:
        Autistic children
        Language acquisition
        Physiology
        Psychology
        Autism
        Vocabulary
        Children
        Means of communication for autistic children
        Word recognition
        Vocabulary ability testing
        Statistical correlation
        Electrodes
        Electroencephalography
        Evoked potentials (Electrophysiology)
        Parietal lobe
        Probability theory
        Questionnaires
        Regression analysis
        Research
        Research funding
        Statistics
        T-test (Statistics)
        Temporal lobe
        Data analysis
        Phonological awareness
        Data analysis software
        Descriptive statistics
      sug:
        subj:
          Autistic children
          Language acquisition
          Physiology
          Psychology
          Autism
          Vocabulary
          Children
          Means of communication for autistic children
          Word recognition
          Vocabulary ability testing
          Statistical correlation
          Electrodes
          Electroencephalography
          Evoked potentials (Electrophysiology)
          Parietal lobe
          Probability theory
          Questionnaires
          Regression analysis
          Research
          Research funding
          Statistics
          T-test (Statistics)
          Temporal lobe
          Data analysis
          Phonological awareness
          Data analysis software
          Descriptive statistics
      ab: Purpose: This investigation was conducted to determine whether young children with autism spectrum disorders exhibited a canonical neural response to word stimuli and whether putative event-related potential (ERP) measures of word processing were correlated with a concurrent measure of receptive language. Additional exploratory analyses were used to examine whether the magnitude of the association between ERP measures of word processing and receptive language varied as a function of the number of word stimuli the participants reportedly understood. Method: Auditory ERPs were recorded in response to spoken words and nonwords presented with equal probability in 34 children aged 2-5 years with a diagnosis of autism spectrum disorder who were in the early stages of language acquisition. Average amplitudes and amplitude differences between word and nonword stimuli within 200-500 ms were examined at left temporal (T3) and parietal (P3) electrode clusters. Receptive vocabulary size and the number of experimental stimuli understood were concurrently measured using the MacArthur- Bates Communicative Development Inventories. Results: Across the entire participant group, word-nonword amplitude differences were diminished. The average word- nonword amplitude difference at T3 was related to receptive vocabulary only if 5 or more word stimuli were understood. Conclusions: If ERPs are to ever have clinical utility, their construct validity must be established by investigations that confirm their associations with predictably related constructs. These results contribute to accruing evidence, suggesting that a valid measure of auditory word processing can be derived from the left temporal response to words and nonwords. In addition, this measure can be useful even for participants who do not reportedly understand all of the words presented as experimental stimuli, though it will be important for researchers to track familiarity with word stimuli in future investigations.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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