CT Perfusion evaluation of gastric cancer: correlation with histologic type.
Objectives: To prospectively evaluate if the perfusion parameters of gastric cancer can provide information on histologic subtypes of gastric cancer.Methods: We performed preoperative perfusion CT (PCT) and curative gastrectomy in 46 patients. PCT data were analysed using a dedicated software progra...
| Published in: | European Radiology Vol. 28; no. 2; pp. 487 - 496 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Feb2018
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=126970469&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 126970469 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2018 vid: 28 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 126970469 126970469 143964814 NLM28779403 10.1007/s00330-017-4979-5 NLM28779403 126970469 ppf: 487 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: CT Perfusion evaluation of gastric cancer: correlation with histologic type. aug: au: Lee, Dong Ho Kim, Se Hyung Joo, Ijin Han, Joon Koo affil: Department of Radiology, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea sug: subj: Neoplasm Staging Stomach Neoplasms Diagnosis Tomography, X-Ray Computed Methods Male Middle Age Aged Diagnosis, Differential ROC Curve Female Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: To prospectively evaluate if the perfusion parameters of gastric cancer can provide information on histologic subtypes of gastric cancer.Methods: We performed preoperative perfusion CT (PCT) and curative gastrectomy in 46 patients. PCT data were analysed using a dedicated software program. Perfusion parameters were obtained by two independent radiologists and were compared according to histologic type using Kruskal-Wallis, Mann-Whitney U test and receiver operating characteristic analysis. To assess inter-reader agreement, we used intraclass correlation coefficient (ICC).Results: Inter-reader agreement for perfusion parameters was moderate to substantial (ICC = 0.585-0.678). Permeability surface value of poorly cohesive carcinoma (PCC) was significantly higher than other histologic types (47.3 ml/100 g/min in PCC vs 26.5 ml/100 g/min in non-PCC, P < 0.001). Mean transit time (MTT) of PCC was also significantly longer than non-PCC (13.0 s in PCC vs 10.3 s in non-PCC, P = 0.032). The area under the curve to predict PCC was 0.891 (P < 0.001) for permeability surface and 0.697 (P = 0.015) for MTT.Conclusion: Obtaining perfusion parameters from PCT was feasible in gastric cancer patients and can aid in the preoperative imaging diagnosis of PCC-type gastric cancer as the permeability surface and MTT value of PCC type gastric cancer were significantly higher than those of non-PCC.Key Points: • Obtaining perfusion parameters from PCT was feasible in patients with gastric cancer. • Permeability surface and MTT were significantly higher in poorly cohesive carcinoma (PCC). • Permeability surface, MTT can aid in the preoperative imaging diagnosis of PCC. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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