Helicobacter pylori infection is positively associated with an increased BMI, irrespective of socioeconomic status and other confounders: a cohort study.
Background: Data on the association of Helicobacter pylori infection and BMI are conflicting. The fact that both H. pylori infection and BMI are associated with low socioeconomic status (SES) makes this relationship difficult to characterize.Materials and Methods: We aimed to evaluate the associatio...
| Publicado en: | European Journal of Gastroenterology & Hepatology Vol. 30; no. 2; pp. 143 - 149 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Feb2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127013705&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127013705 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0954691X 8CE jtl: European Journal of Gastroenterology & Hepatology issn: 0954691X maglogo: N pubinfo: dt: Feb2018 vid: 30 iid: 2 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 127013705 127013705 NLM29120907 127013705 10.1097/MEG.0000000000001014 NLM29120907 127013705 ppf: 143 ppct: 6 formats: tig: atl: Helicobacter pylori infection is positively associated with an increased BMI, irrespective of socioeconomic status and other confounders: a cohort study. aug: au: Suki, Mohamad Weissman, Yaara Leibovici Boltin, Doron Itskoviz, David Perets, Tsachi Tsadok Comaneshter, Doron Cohen, Arnon Niva, Yaron Dotan, Iris Leibovitzh, Haim Levi, Zohar Leibovici Weissman, Yaara Tsadok Perets, Tsachi Niv, Yaron affil: Department of Gastroenterology, Rabin Medical Center, Beilinson Campus, PetachTikva, Israel sug: subj: Helicobacter Pylori Thinness Epidemiology Obesity Epidemiology Body Mass Index Helicobacter Infections Epidemiology Helicobacter Infections Ethnology Social Class Male Helicobacter Infections Diagnosis Adult Body Weight Israel Middle Age Arabs Statistics and Numerical Data Jews Statistics and Numerical Data Prevalence Breath Tests Aged Female Human Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Data on the association of Helicobacter pylori infection and BMI are conflicting. The fact that both H. pylori infection and BMI are associated with low socioeconomic status (SES) makes this relationship difficult to characterize.Materials and Methods: We aimed to evaluate the association between BMI and H. pylori infection after adjusting for multiple covariates. We analyzed a cohort of 235 107 individuals aged 18 years or older, who performed a C urease breath test (C-UBT), from 2007 to 2014. Data on BMI, age, sex, SES, ethnicity, and medications were extracted from a nationwide population-based database. BMIs were classified according to the WHO recommendations: underweight (<18.5 kg/m), normal weight (18.5-24.9 kg/m), overweight (25-29.9 kg/m), obese class I (30-34.9 kg/m), and obese class II or more (>35 kg/m).Study Results: The positivity rate for H. pylori among underweight, normal weight, overweight, and obese class I and class II or more was 55.6, 58.5, 63.0, 64.5, and 65.5%, respectively (P<0.001, Plinear trend 0.007). The association between BMI and H. pylori infection was significant across all SES, sex, ethnicity, and age categories. After adjusting for age, sex, ethnicity, and SES, being overweight and obese class I and class II or more were associated significantly with H. pylori positivity: odds ratio 1.13 [95% confidence interval (CI): 1.11-1.15], 1.14 (95% CI: 1.11-1.17), and 1.15 (95% CI: 1.11-1.19), respectively, P value less than 0.001 for all.Conclusion: Among individuals who were referred to a C-UBT by primary care physician, after adjusting for multiple covariates including SES, we found a positive association between H. pylori infection and an increased BMI. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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