The 5-HT receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers.

Rationale: Brain 5-HT receptors form part of a neural network that controls eating behaviour. 5-HT receptor agonists decrease food intake by activating proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus, but recent research in rodents has suggested that 5-HT receptor agoni...

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Detalles Bibliográficos
Publicado en:Psychopharmacology Vol. 235; no. 1; pp. 257 - 268
Autores principales: Thomas, Jason M., Dourish, Colin T., Tomlinson, Jeremy, Hassan-Smith, Zaki, Hansen, Peter C., Higgs, Suzanne
Formato: Journal Article
Publicado: Springer Nature Jan2018
Acceso en línea:Ver este registro en EBSCOhost