Research on Ratio of Dosage of Drugs in Traditional Chinese Prescriptions by Data Mining...The 16th World Congress of Medical and Health Informatics: Precision Healthcare Through Informatics (MedInfo2017); Hangzhou, China; August 21st to 25th, 2017.

Maximizing the effectiveness of prescriptions and minimizing adverse effects of drugs is a key component of the health care of patients. In the practice of traditional Chinese medicine (TCM), it is important to provide clinicians a reference for dosing of prescribed drugs. The traditional Cheng-Chur...

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Detalles Bibliográficos
Publicado en:Studies in Health Technology & Informatics Vol. 245; pp. 653 - 657
Autores principales: Yu Xing-wen, Gong Qing-yue, Hu Kong-fa, Mao Wen-jing, Zhang Wei-ming
Formato: equations & formulas proceedings research tables/charts Journal Article
Publicado: Sage Publications Inc. 2017
Acceso en línea:Ver este registro en EBSCOhost
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Sumario:Maximizing the effectiveness of prescriptions and minimizing adverse effects of drugs is a key component of the health care of patients. In the practice of traditional Chinese medicine (TCM), it is important to provide clinicians a reference for dosing of prescribed drugs. The traditional Cheng-Church biclustering algorithm (CC) is optimized and the data of TCM prescription dose is analyzed by using the optimization algorithm. Based on an analysis of 212 prescriptions related to TCM treatment of kidney diseases, the study generated 87 prescription dose quantum matrices and each sub-matrix represents the referential value of the doses of drugs in different recipes. The optimized CC algorithm can effectively eliminate the interference of zero in the original dose matrix of TCM prescriptions and avoid zero appearing in output sub-matrix. This results in the ability to effectively analyze the reference value of drugs in different prescriptions related to kidney diseases, so as to provide valuable reference for clinicians to use drugs rationally.