Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model.

Background: Disseminated tumor cells (DTCs) found in the bone marrow (BM) of patients with breast cancer portend a poor prognosis and are thought to be intermediaries in the metastatic process. To assess the clinical relevance of a mouse model for identifying possible prognostic and predictive bioma...

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Bibliographic Details
Published in:Breast Cancer Research Vol. 20; pp. 1 - 13
Main Authors: Pillai, Sreeraj G., Li, Shunqiang, Siddappa, Chidananda M., Ellis, Matthew J, Watson, Mark A., Aft, Rebecca
Format: research Journal Article
Published: BioMed Central 1/2/2018
Online Access:View this record in EBSCOhost