Correlation Filters for Detection of Cellular Nuclei in Histopathology Images.

Nuclei detection in histology images is an essential part of computer aided diagnosis of cancers and tumors. It is a challenging task due to diverse and complicated structures of cells. In this work, we present an automated technique for detection of cellular nuclei in hematoxylin and eosin stained...

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Publicado en:Journal of Medical Systems Vol. 42; no. 1; pp. 1 - 9
Autores principales: Ahmad, Asif, Asif, Amina, Rajpoot, Nasir, Arif, Muhammad, Minhas, Fayyaz ul Amir Afsar
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jan2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-017-0863-8
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        atl: Correlation Filters for Detection of Cellular Nuclei in Histopathology Images.
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          Ahmad, Asif
          Asif, Amina
          Rajpoot, Nasir
          Arif, Muhammad
          Minhas, Fayyaz ul Amir Afsar
        affil: Biomedical Informatics Research Laboratory, Department of Computer and Information Sciences, Pakistan Institute of Engineering and Applied Sciences, PO Nilore, Islamabad, Pakistan
      sug:
        subj:
          Cell Physiology
          Image Interpretation, Computer Assisted
          Human
          Image Processing, Computer Assisted
          Colorectal Neoplasms
      ab: Nuclei detection in histology images is an essential part of computer aided diagnosis of cancers and tumors. It is a challenging task due to diverse and complicated structures of cells. In this work, we present an automated technique for detection of cellular nuclei in hematoxylin and eosin stained histopathology images. Our proposed approach is based on kernelized correlation filters. Correlation filters have been widely used in object detection and tracking applications but their strength has not been explored in the medical imaging domain up till now. Our experimental results show that the proposed scheme gives state of the art accuracy and can learn complex nuclear morphologies. Like deep learning approaches, the proposed filters do not require engineering of image features as they can operate directly on histopathology images without significant preprocessing. However, unlike deep learning methods, the large-margin correlation filters developed in this work are interpretable, computationally efficient and do not require specialized or expensive computing hardware. Availability: A cloud based webserver of the proposed method and its python implementation can be accessed at the following URL: .
      pubtype: Academic Journal
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        equations & formulas
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    language: English
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