A Novel Adaptive Deformable Model for Automated Optic Disc and Cup Segmentation to Aid Glaucoma Diagnosis.

This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region...

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Publicado en:Journal of Medical Systems Vol. 42; no. 1; pp. 1 - 19
Autores principales: Haleem, Muhammad Salman, Han, Liangxiu, Hemert, Jano van, Li, Baihua, Fleming, Alan, Pasquale, Louis R., Song, Brian J.
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jan2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-017-0859-4
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        atl: A Novel Adaptive Deformable Model for Automated Optic Disc and Cup Segmentation to Aid Glaucoma Diagnosis.
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          Haleem, Muhammad Salman
          Han, Liangxiu
          Hemert, Jano van
          Li, Baihua
          Fleming, Alan
          Pasquale, Louis R.
          Song, Brian J.
        affil: School of Computing, Mathematics and Digital Technology, Manchester Metropolitan University, M1 5GD, Manchester, UK
      sug:
        subj:
          Glaucoma Diagnosis
          Image Processing, Computer Assisted
          Human
          Female
          Male
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          ROC Curve
          P-Value
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region Classification Model (RCM) in a pixel-level multidimensional feature space; 2) an Adaptive Edge Smoothing Update model (AESU) of contour points (e.g. misclassified or irregular points) based on iterative force field calculations with contours obtained from the RCM by minimising energy function (an approach that does not require predefined geometric templates to guide auto-segmentation). Such an approach provides robustness in capturing a range of variations and shapes. We have conducted a comprehensive comparison between our approach and the state-of-the-art existing deformable models and validated it with publicly available datasets. The experimental evaluation shows that the proposed approach significantly outperforms existing methods. The generality of the proposed approach will enable segmentation and detection of other object boundaries and provide added value in the field of medical image processing and analysis.
      pubtype: Academic Journal
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        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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