Dosimetric comparison of 3-dimensional conformal radiotherapy, volumetric modulated arc therapy, and helical tomotherapy for postoperative gastric cancer patients.

Purpose: To compare dosimetric data for the planning target volume (PTV) and organs at risk (OARs) between 3-dimensional conformal radiotherapy (3DCRT), volumetric modulated arc therapy (VMAT), and helical tomotherapy [1].Materials and Methods: The dosimetric data for 15 gastric cancer patients trea...

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Publicado en:Japanese Journal of Radiology Vol. 36; no. 1; pp. 30 - 40
Autores principales: Onal, Cem, Dölek, Yemliha, Akkuş Yıldırım, Berna
Formato: research Journal Article
Publicado: Springer Nature Jan2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2018
      vid: 36
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11604-017-0696-x
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        atl: Dosimetric comparison of 3-dimensional conformal radiotherapy, volumetric modulated arc therapy, and helical tomotherapy for postoperative gastric cancer patients.
      aug:
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          Onal, Cem
          Dölek, Yemliha
          Akkuş Yıldırım, Berna
        affil: Department of Radiation Oncology, Adana Dr Turgut Noyan Research and Treatment Centre, Baskent University Faculty of Medicine, 01120, Adana, Turkey
      sug:
        subj:
          Radiotherapy, Computer-Assisted Methods
          Radiotherapy, Conformal Methods
          Stomach Neoplasms Radiotherapy
          Postoperative Period
          Middle Age
          Aged
          Adult
          Male
          Human
          Body Regions
          Radiation Dosage
          Radiometry
          Female
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Middle Aged: 45-64 years
          Aged: 65+ years
          Adult: 19-44 years
          Male
          Female
      ab: Purpose: To compare dosimetric data for the planning target volume (PTV) and organs at risk (OARs) between 3-dimensional conformal radiotherapy (3DCRT), volumetric modulated arc therapy (VMAT), and helical tomotherapy [1].Materials and Methods: The dosimetric data for 15 gastric cancer patients treated with 3DCRT, VMAT, or HT techniques were used. Cumulative dosimetric parameters, homogeneity index (HI), and conformal index (CI) were compared for the PTV and OARs.Results: The average maximum doses of PTV were significantly higher in VMAT plans than in 3DCRT (p = 0.04) and HT (p = 0.02) plans, whereas minimum dose values were significantly lower in 3DCRT plans compared with VMAT (p < 0.001) and HT (p = 0.02) plans. Liver mean dose (D mean) and D mean values for both kidneys were significantly lower in HT plans than in 3DCRT and VMAT plans. The doses in high dose regions (V30-V45) using 3DCRT plans were significantly higher compared to both VMAT and HT plans. The bowel V5-V30 and V45 was significantly less in HT plans compared to VMAT plans. There were no significant differences in dose sparing of the spinal cord.Conclusions: The HT plans reduced the maximum dose applied to the target and improved the conformality and homogeneity of radiation, while providing sufficient PTV coverage.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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