Cover Image
QR Code

Emerging Scientist: Vocal Fold Immunology.

In adults the immune system is intimately involved in restoring function lost after injury. If it is poorly regulated, the initial protective reactions that encompass wound healing can lead to pathologic changes in the vocal fold that are particularly problematic to voice quality. Inflammatory injur...

Full description

Published in:Perspectives of the ASHA Special Interest Groups Vol. 1; no. 3; pp. 26 - 33
Main Author: King, Suzanne N.
Format: review tables/charts Journal Article
Published: American Speech-Language-Hearing Association 2016
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127269935&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 127269935
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        2381473X
        KTSD
      jtl: Perspectives of the ASHA Special Interest Groups
      issn: 2381473X
      maglogo: N
    pubinfo:
      dt: 2016
      vid: 1
      iid: 3
      pid: 42
      pub: American Speech-Language-Hearing Association
      place: Rockville, Maryland
    artinfo:
      ui:
        127269935
        127269935
        127269935
        10.1044/persp1.SIG3.26
        127269935
      ppf: 26
      ppct: 7
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Emerging Scientist: Vocal Fold Immunology.
      aug:
        au: King, Suzanne N.
        affil: Department of Neurological Surgery, Kentucky Spinal Cord Injury Research Center, University of Louisville Louisville, KY
      sug:
        subj:
          Vocal Cords Injuries
          Vocal Cords Physiopathology
          Vocal Cords Immunology
          Immune System Physiology
          Wound Healing
          Cells Classification
          Regeneration
      ab: In adults the immune system is intimately involved in restoring function lost after injury. If it is poorly regulated, the initial protective reactions that encompass wound healing can lead to pathologic changes in the vocal fold that are particularly problematic to voice quality. Inflammatory injuries can contribute to pathophysiology of benign vocal fold lesions or scarring. Cells and molecules of the innate immune system are responsible for fighting off challenges and returning the tissue to its pre-injured state. This review briefly discusses aspects of the immune system with a focus on acute inflammation and confers immunological barriers to biomaterial and cell-based approaches for restoration of the voice. Increasing the awareness of laryngeal immunology will facilitate better understanding of the obstacles being faced in bench research and highlight the need for further work.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N