Rhabdomyolysis following Cardiac Surgery: A Prospective, Descriptive, Single-Center Study.
Purpose. Rhabdomyolysis (RML) following cardiac surgery and its relationship with acute kidney injury (AKI) require investigation. Patients and Methods. All patients undergoing cardiac surgery in our hospital were enrolled in this prospective study during a 1-year period. To investigate the occurren...
| Published in: | BioMed Research International Vol. 2016; pp. 1 - 8 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Wiley-Blackwell
2/29/2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127439468&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127439468 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2/29/2016 vid: 2016 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 127439468 10.1155/2016/7497936 127439468 ppf: 1 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Rhabdomyolysis following Cardiac Surgery: A Prospective, Descriptive, Single-Center Study. aug: au: Omar, Amr S. Ewila, Hesham Aboulnaga, Sameh Tuli, Alejandro Kohn Singh, Rajvir affil: Department of Cardiothoracic Surgery/Cardiac Anaesthesia & ICU Section, Heart Hospital, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar. sug: ab: Purpose. Rhabdomyolysis (RML) following cardiac surgery and its relationship with acute kidney injury (AKI) require investigation. Patients and Methods. All patients undergoing cardiac surgery in our hospital were enrolled in this prospective study during a 1-year period. To investigate the occurrence of RML and its association with AKI, all patients in the study underwent serial assessment of serum creatine kinase (CK) and myoglobin levels. Serial renal function, prior statin treatment, and outcome variables were recorded. Results. In total, 201 patients were included in the study: 185 men and 16 women with a mean age of 52.0 ± 12.4 years. According to the presence of RML (CK of ≥2,500 U/L), the patients were divided into Group I (RML present in 17 patients) and Group II (RML absent in 184 patients). Seven patients in Group I had AKI (41%) where 34 patients in group II had AKI (18.4%), 𝑃 = 0.025. We observed a significantly longer duration of ventilation, length of stay in the ICU, and hospitalization in Group I (𝑃 < 0.001 for all observations). Conclusions. An early elevation of serum CK above 2500 U/L postoperatively in high-risk cardiac surgery could be used to diagnose RML that may predict the concomitance of early AKI. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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