Microfluidic Emulation of Mechanical Circulatory Support Device Shear-Mediated Platelet Activation.

Thrombosis of ventricular assist devices (VADs) compromises their performance, with associated risks of systemic embolization, stroke, pump stop and possible death. Anti-thrombotic (AT) drugs, utilized to limit thrombosis, are largely dosed empirically, with limited testing of their efficacy. Furthe...

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Bibliographic Details
Published in:Biomedical Microdevices Vol. 17; no. 6; pp. 1 - 25
Main Authors: Dimasi, A., Rasponi, M., Sheriff, J., Chiu, W.-C., Bluestein, D., Tran, P. L., Slepian, M. J., Redaelli, A.
Format: Journal Article
Published: Springer Nature Dec2015
Online Access:View this record in EBSCOhost