Variability in Ultrasound Backscatter Induced by Trabecular Microstructure Deterioration in Cancellous Bone.

To determine the relationship between the ultrasonic backscatter parameters and trabecular microstructural variations in cancellous bone, three erosion procedures were performed to simulate various changes in the cancellous bone microstructure. The finite difference time domain (FDTD) method was use...

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Publicado en:BioMed Research International Vol. 2018; pp. 1 - 8
Autores principales: Chou, Xingxing, Xu, Feng, Li, Ying, Liu, Chengcheng, Ta, Dean, Le, Lawrence H.
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 1/29/2018
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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      dt: 1/29/2018
      vid: 2018
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        127636858
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        10.1155/2018/4786329
        127636858
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        atl: Variability in Ultrasound Backscatter Induced by Trabecular Microstructure Deterioration in Cancellous Bone.
      aug:
        au:
          Chou, Xingxing
          Xu, Feng
          Li, Ying
          Liu, Chengcheng
          Ta, Dean
          Le, Lawrence H.
        affil: Department of Electronic Engineering, Fudan University, Shanghai 200433, China
      sug:
        subj:
          Cancellous Bone Pathology
          Cancellous Bone Ultrasonography
          Human
          Linear Regression
          Computer Simulation
      ab: To determine the relationship between the ultrasonic backscatter parameters and trabecular microstructural variations in cancellous bone, three erosion procedures were performed to simulate various changes in the cancellous bone microstructure. The finite difference time domain (FDTD) method was used to simulate the backscatter signal in cancellous bone. Ultrasonic backscatter properties were derived as functions of the porosity when the ultrasound incident directions were perpendicular and parallel to the major trabeculae direction (MTD), respectively. The variability in the apparent backscatter coefficient (ABC) and apparent integrated backscatter (AIB) due to the trabecular microstructure was revealed. Significant negative correlations between the backscatter parameters (ABC and AIB) and the porosity of the cancellous bone were observed. The simulations showed that the ABC and AIB were influenced by the direction of the trabecular microstructural variations. The linear regressions between the ultrasonic backscatter parameters (ABC and AIB) and the porosity showed significantly different slopes for three erosion procedures when they are ultrasonically perpendicular (for ABC, −1.22 dB, −0.98 dB, and −0.46 dB; for AIB, −0.74 dB, −0.69 dB, and −0.25 dB) and parallel (for ABC, −1.87 dB, −0.69 dB, and −0.51 dB; for AIB, −0.9 dB, −0.5 dB, and −0.34 dB) to the MTD. This paper investigated the relationship between ultrasonic backscatter and cancellous bone microstructure deterioration and indicated that the ultrasonic backscatter could be affected by cancellous bone microstructure deterioration direction.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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