Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma.

<italic>Purpose</italic>. To compare optical coherence tomography angiography (OCT-A) and laser speckle flowgraphy (LSFG) for the diagnosis of normal-tension glaucoma (NTG). <italic>Methods</italic>. Twenty-eight eyes of 28 patients with NTG and 25 eyes of 25 normal subjects matched for age, refract...

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Publicado en:Journal of Ophthalmology pp. 1 - 10
Autores principales: Takeyama, Asuka, Ishida, Kyoko, Anraku, Ayako, Ishida, Masahiro, Tomita, Goji
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 1/31/2018
Acceso en línea:Ver este registro en EBSCOhost
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        2090004X
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      jtl: Journal of Ophthalmology
      issn: 2090004X
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      dt: 1/31/2018
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        127695463
        127695463
        127695463
        10.1155/2018/1751857
        127695463
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        atl: Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma.
      aug:
        au:
          Takeyama, Asuka
          Ishida, Kyoko
          Anraku, Ayako
          Ishida, Masahiro
          Tomita, Goji
        affil: Department of Ophthalmology, Teikyo University Hospital, Mizonokuchi, Kawasaki, Japan
      sug:
        subj:
          Blood Flow Velocity Evaluation
          Angiography Methods
          Glaucoma Diagnosis
          Optic Nerve Blood Supply
          Blood Circulation Evaluation
          Tomography, Optical Coherence Methods
          Human
          Intraocular Pressure
          Glaucoma Physiopathology
          Refractive Errors
          Blood Pressure
          Descriptive Statistics
          Cornea Pathology
          ROC Curve
          Optic Nerve Pathology
      ab: <italic>Purpose</italic>. To compare optical coherence tomography angiography (OCT-A) and laser speckle flowgraphy (LSFG) for the diagnosis of normal-tension glaucoma (NTG). <italic>Methods</italic>. Twenty-eight eyes of 28 patients with NTG and 25 eyes of 25 normal subjects matched for age, refractive errors, systemic blood pressure, and central corneal thickness were evaluated. OCT-A was used to measure whole image vessel density, inside disc vessel density, and peripapillary vessel density; using LSFG, mean blur rate (MBR) inside the whole optic nerve head (ONH) area (MBRA), and MBR of the vessel area (MBRV) and tissue area (MBRT) inside the ONH, were determined. Receiver operating characteristic (ROC) curves and areas under the ROC (AUROC) were used to assess the diagnostic ability of each variable. <italic>Results</italic>. The AUROC for OCT-A whole image vessel density (0.950) was significantly greater than that for OCT-A peripapillary vessel density (0.830) and for all LSFG parameters (MBRA = 0.793, MBRV = 0.601, and MBRT = 0.61) (P<0.001). The AUROC for OCT-A inside disc vessel density (0.931) was significantly greater than that for all LSFG parameters (P<0.005). <italic>Conclusions</italic>. OCT-A vessel density had a higher glaucoma diagnostic ability compared to all LSFG parameters in patients with NTG.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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