Estimating the prevalence of diabetes mellitus and thyroid disorders using medication data in Flanders, Belgium.

Background: Various methods exist to estimate disease prevalences. The aim of this study was to determine whether dispensed, self-reported and prescribed medication data could be used to estimate the prevalence of diabetes mellitus and thyroid disorders. Second, these pharmaco-epidemiological estima...

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Publicado en:European Journal of Public Health Vol. 28; no. 1; pp. 193 - 199
Autores principales: Vaes, Bert, Ruelens, Catherine, Saikali, Samuel, Smets, Alexander, Henrard, Séverine, Renard, Francoise, den Akker, Marjan van, Van Pottelbergh, Gijs, Goderis, Geert, Van der Heyden, Johan
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Feb2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2018
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        atl: Estimating the prevalence of diabetes mellitus and thyroid disorders using medication data in Flanders, Belgium.
      aug:
        au:
          Vaes, Bert
          Ruelens, Catherine
          Saikali, Samuel
          Smets, Alexander
          Henrard, Séverine
          Renard, Francoise
          den Akker, Marjan van
          Van Pottelbergh, Gijs
          Goderis, Geert
          Van der Heyden, Johan
        affil: Department of Public Health and Primary Care, University of Leuven (KU Leuven), Leuven, Belgium
      sug:
        subj:
          Diabetes Mellitus Epidemiology
          Thyroid Diseases Epidemiology
          Self Report
          Prescriptions, Drug Statistics and Numerical Data
          Human
          Prevalence
          Belgium
          Surveys
          Patient Record Systems
          Diabetes Mellitus Diagnosis
          Thyroid Diseases Diagnosis
          Sensitivity and Specificity
          Descriptive Research
          Cross Sectional Studies
          Interviews
      ab: Background: Various methods exist to estimate disease prevalences. The aim of this study was to determine whether dispensed, self-reported and prescribed medication data could be used to estimate the prevalence of diabetes mellitus and thyroid disorders. Second, these pharmaco-epidemiological estimates were compared with prevalences based on self-reported diagnoses and doctor-registered diagnoses. Methods: Data on medication for diabetes and thyroid disorders were obtained from three different sources in Flanders (Belgium) for 2008: a purely administrative database containing data on dispensed medication, the Belgian National Health Interview Survey for self-reported medication and diagnoses, and a patient record database for prescribed medication and doctor- registered diagnoses. Prevalences were estimated based on medication data and compared with each other. Cross-tabulations of dispensed medication and self-reported diagnoses, and prescribed medication and doctor-registered diagnoses, were investigated. Results: Prevalences based on dispensed medication were the highest (4.39 and 2.98% for diabetes and thyroid disorders, respectively). The lowest prevalences were found using prescribed medication (2.39 and 1.72%, respectively). Cross-tabulating dispensed medication and self-reported diagnoses yielded a moderate to high sensitivity for diabetes (90.4%) and thyroid disorders (77.5%), while prescribed medication showed a low sensitivity for doctor-registered diagnoses (56.5 and 43.6%, respectively). The specificity remained above 99% in all cases. Conclusions: This study was the first to perform cross-tabulations for disease prevalence estimates between different databases and within (sub)populations. Purely administrative database was shown to be a reliable source to estimate disease prevalence based on dispensed medication. Prevalence estimates based on prescribed or self-reported medication were shown to have important limitations.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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