Testicular ultrasensitive Doppler preliminary experience: a feasibility study.

Background Ultrasensitive Doppler is a novel non-invasive ultrasound (US) Doppler technique that improves sensitivity and resolution for the detection of slow flow. Purpose To investigate the feasibility of ultrasensitive Doppler (USD) for testicular disease diagnosis, using both qualitative and qua...

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Publicado en:Acta Radiologica Vol. 59; no. 3; pp. 346 - 355
Autores principales: Rocher, Laurence, Gennisson, Jean-Luc, Ferlicot, Sophie, Criton, Aline, Albiges, Laurence, Izard, Vincent, Bellin, Marie France, Correas, Jean-Michel
Formato: diagnostic images pictorial research Journal Article
Publicado: Sage Publications Inc. Mar2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2018
      vid: 59
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      pub: Sage Publications Inc.
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        atl: Testicular ultrasensitive Doppler preliminary experience: a feasibility study.
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        au:
          Rocher, Laurence
          Gennisson, Jean-Luc
          Ferlicot, Sophie
          Criton, Aline
          Albiges, Laurence
          Izard, Vincent
          Bellin, Marie France
          Correas, Jean-Michel
        affil: Department of Adult Diagnostic and Interventional Radiology, Bicetre University Hospital, Le Kremlin Bicêtre, France
      sug:
        subj:
          Ultrasonography, Doppler Methods
          Testicular Diseases
          Scrotum
          Reproducibility of Results
          Aged, 80 and Over
          Adolescence
          Adult
          Middle Age
          Young Adult
          Prospective Studies
          Male
          Sensitivity and Specificity
          Aged
          Pilot Studies
          Human
          Aged, 80 & over
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
      ab: Background Ultrasensitive Doppler is a novel non-invasive ultrasound (US) Doppler technique that improves sensitivity and resolution for the detection of slow flow. Purpose To investigate the feasibility of ultrasensitive Doppler (USD) for testicular disease diagnosis, using both qualitative and quantitative results. Material and Methods This prospective study was conducted in 160 successive men referred for scrotal US including B-mode and conventional Color-Doppler. A new USD sequence and algorithm dedicated to academic research were implemented into the US system. The quality criterion for a successful examination was the detection of well delineated intratesticular vessels. Qualitative USD results were described in terms of tumor vascular architecture and flow intensity for different pathologies for 41 patients. The testicular vascularization (TV), defined as a vessel's surface ratio, was quantified using customized MATLAB® software and compared in azoospermic and normal patients. Results USD was acquired successfully in 153/160 patients (95.6%). The tumor vascular architecture differed depending on the nature of the tumors. Leydig cell tumors exhibited mostly circumferential vascularization, while germ cell tumors exhibited straight vessels through the tumors, or anarchic vascular maps. USD improved the diagnostic performance of testicular Doppler US in a case of incomplete spermatic cord torsion and acute epididymitis. The reproducibility of TV measurements established an interclass correlation of 0.801. Non-Klinefelter syndrome non-obstructive azoospermia patients exhibited a lower TV compared to normal patients, to Klinefelter syndrome, and to obstructive azoospermia patients ( P < 0.002, P < 0.005, and P < 0.05, respectively). Conclusion Testicular USD can become a promising technique for improving US diagnosis of tumors, acute scrotum, and for determining infertility status.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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