Atrial deformation correlated with functional capacity in mitral stenosis patients.

Background: Left atrial (LA) dysfunction, expressed as impaired LA deformation using two‐dimensional (2D) strain imaging, has been observed in association with rheumatic mitral stenosis (MS). However, the clinical role of speckle tracking echocardiography (STE)‐derived LA strain has rarely been stud...

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Published in:Echocardiography Vol. 35; no. 2; pp. 190 - 196
Main Authors: Chien, Chen‐Yu, Chen, Chih‐Wei, Lin, Tin‐Kwang, Lin, Yu, Lin, Jnnu‐Wen, Li, Yi‐Da, Chen, Chi‐Hsien, Tsai, Wei‐Chuan
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell Feb2018
Online Access:View this record in EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Atrial deformation correlated with functional capacity in mitral stenosis patients.
      aug:
        au:
          Chien, Chen‐Yu
          Chen, Chih‐Wei
          Lin, Tin‐Kwang
          Lin, Yu
          Lin, Jnnu‐Wen
          Li, Yi‐Da
          Chen, Chi‐Hsien
          Tsai, Wei‐Chuan
        affil: Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan
      sug:
        subj:
          Mitral Valve Stenosis
          Heart Failure
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Echocardiography, Doppler, Color
          Descriptive Statistics
          Data Analysis Software
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Left atrial (LA) dysfunction, expressed as impaired LA deformation using two‐dimensional (2D) strain imaging, has been observed in association with rheumatic mitral stenosis (MS). However, the clinical role of speckle tracking echocardiography (STE)‐derived LA strain has rarely been studied in MS. Aim: This study aimed to identify the determinants of New York Heart Association (NYHA) functional class in patients with mitral stenosis and to investigate the relationship between left atrial deformation as measured by two‐dimensional STE‐derived LA strain and heart failure symptoms. Methods: Sixty‐nine consecutive patients (20 males and 49 females; mean age: 61 ± 14 years) with rheumatic MS were evaluated using comprehensive 2D and color Doppler echocardiography including STE‐derived LA strain (LAS) and peak positive filling strain rate (LASRr) during the LA reservoir phase. Those results were then correlated with NYHA functional class. Results: There were 15 (22%) patients in functional class I, 42 (61%) in functional class II, and 12 (17%) in functional class III. There were no significant differences in mitral valve area, pressure gradient, pulmonary artery pressure, LA emptying fraction, or left ventricular ejection fraction between functional classes. Upon multivariate analysis (controlling for diuretics usage), LAS (ß = −0.233, <italic>P</italic> = .045) and LASRr (ß = −0.277, <italic>P</italic> = .014) were independent factors in determining NYHA functional class. Conclusions: In stable patients with MS, NYHA functional class independently correlated with LAS and LASRr. Left atrial (LA) deformation correlated with heart failure symptoms in patients with MS.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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