Gender differences in mortality among ST elevation myocardial infarction patients in Malaysia from 2006 to 2013.
Background: Coronary artery disease (CAD) is one of the leading causes of death in Malaysia. However, the prevalence of CAD in males is higher than in females and mortality rates are also different between the two genders. This suggest that risk factors associated with mortality between males and fe...
| Publicado en: | Annals of Saudi Medicine Vol. 38; no. 1; pp. 481 - 488 |
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| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
Association of Arab Universities
Jan/Feb2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127951913&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127951913 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02564947 IKW jtl: Annals of Saudi Medicine issn: 02564947 maglogo: N pubinfo: dt: Jan/Feb2018 vid: 38 iid: 1 pid: 55627 pub: Association of Arab Universities place: Great Neck, New York artinfo: ui: 127951913 127951913 NLM29419522 10.5144/0256-4947.2018.1 NLM29419522 127951913 ppf: 481 ppct: 7 formats: tig: atl: Gender differences in mortality among ST elevation myocardial infarction patients in Malaysia from 2006 to 2013. aug: au: Juhan, Nurliyana Zubairi, Yong Z. Zuhdi, A. S. Khalid, Zarina Mohd Wan Ahmad, Wan Azman Wan, Wan Azman affil: Department of Mathematics, Faculty of Science, Universiti Teknologi Malaysia, Johoor, Malaysia sug: subj: Hospital Mortality Risk Factors Demography Age Factors Retrospective Design Male Middle Age Female Aged Sex Factors Data Collection Malaysia Cardiovascular Care Statistics and Numerical Data Menopause Physiology Scales Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Coronary artery disease (CAD) is one of the leading causes of death in Malaysia. However, the prevalence of CAD in males is higher than in females and mortality rates are also different between the two genders. This suggest that risk factors associated with mortality between males and females are different, so we compared the clinical characteristics and outcome between male and female STEMI patients.Objectives: To identify the risk factors associated with mortality for each gender and compare differences, if any, among ST-elevation myocardial infarction (STEMI) patients.Design: Retrospective analysis.Settings: Hospitals across Malaysia.Patients and Methods: We analyzed data on all STEMI patients in the National Cardiovascular Database-Acute coronary syndrome (NCVD-ACS) registry for the years 2006 to 2013 (8 years). We collected demographic and risk factor data (diabetes mellitus, hypertension, smoking status, dyslipidaemia and family history of CAD). Significant variables from the univariate analysis were further analysed by a multivariate logistic analysis to identify risk factors and compare by gender.Main Outcome Measures: Differential risk factors for each gender.Results: For the 19484 patients included in the analysis, the mortality rate over the 8 years was significantly higher in females (15.4%) than males (7.5%) (P < .001). The univariate analysis showed that the majority of male patients < 65 years while females were >=65 years. The most prevalent risk factors for male patients were smoking (79.3%), followed by hypertension (54.9%) and diabetes mellitus (40.4%), while the most prevalent risk factors for female patients were hypertension (76.8%), followed by diabetes mellitus (60%) and dyslipidaemia (38.1%). The final model for male STEMI patients had seven significant variables: Killip class, age group, hypertension, renal disease, percutaneous coronary intervention and family history of CVD. For female STEMI patients, the significant variables were renal disease, smoking status, Killip class and age group.Conclusion: Gender differences existed in the baseline characteristics, associated risk factors, clinical presentation and outcomes among STEMI patients. For STEMI females, the rate of mortality was twice that of males. Once they reach menopausal age, when there is less protection from the estrogen hormone and there are other risk factors, menopausal females are at increased risk for STEMI.Limitation: Retrospective registry data with inter-hospital variation. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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