Empirical Wavelet Transform Based Features for Classification of Parkinson’s Disease Severity.

Parkinson’s disease (PD) is a type of progressive neurodegenerative disorder that has affected a large part of the population till now. Several symptoms of PD include tremor, rigidity, slowness of movements and vocal impairments. In order to develop an effective diagnostic system, a number of algori...

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Publicado en:Journal of Medical Systems Vol. 42; no. 2
Autores principales: Oung, Qi Wei, Muthusamy, Hariharan, Basah, Shafriza Nisha, Lee, Hoileong, Vijean, Vikneswaran
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Feb2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-017-0877-2
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          Oung, Qi Wei
          Muthusamy, Hariharan
          Basah, Shafriza Nisha
          Lee, Hoileong
          Vijean, Vikneswaran
        affil: School of Mechatronic Engineering, Universiti Malaysia Perlis (UniMAP), Campus Pauh Putra, 02600, Arau, Perlis, Malaysia
      sug:
        subj:
          Parkinson Disease Classification
          Severity of Illness
          Wearable Sensors
          Human
          Motion Analysis Systems
          Female
          Male
          Middle Age
          Aged
          Speech Disorders
          Biological Markers
          Signal Processing, Computer Assisted
          P-Value
          Analysis of Variance
          Data Analysis Software
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Parkinson’s disease (PD) is a type of progressive neurodegenerative disorder that has affected a large part of the population till now. Several symptoms of PD include tremor, rigidity, slowness of movements and vocal impairments. In order to develop an effective diagnostic system, a number of algorithms were proposed mainly to distinguish healthy individuals from the ones with PD. However, most of the previous works were conducted based on a binary classification, with the early PD stage and the advanced ones being treated equally. Therefore, in this work, we propose a multiclass classification with three classes of PD severity level (mild, moderate, severe) and healthy control. The focus is to detect and classify PD using signals from wearable motion and audio sensors based on both empirical wavelet transform (EWT) and empirical wavelet packet transform (EWPT) respectively. The EWT/EWPT was applied to decompose both speech and motion data signals up to five levels. Next, several features are extracted after obtaining the instantaneous amplitudes and frequencies from the coefficients of the decomposed signals by applying the Hilbert transform. The performance of the algorithm was analysed using three classifiers – K-nearest neighbour (KNN), probabilistic neural network (PNN) and extreme learning machine (ELM). Experimental results demonstrated that our proposed approach had the ability to differentiate PD from non-PD subjects, including their severity level – with classification accuracies of more than 90% using EWT/EWPT-ELM based on signals from motion and audio sensors respectively. Additionally, classification accuracy of more than 95% was achieved when EWT/EWPT-ELM is applied to signals from integration of both signal’s information.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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