Microflow imaging: New Doppler technology to detect low-grade inflammation in patients with arthritis.
Aim: To assess the efficacy of microvascular imaging in detecting low-grade inflammation in arthritis compared with Power Doppler ultrasound (PDUS).Method and Materials: Patients presenting for ultrasound with arthralgia were assessed with grey-scale, PDUS and Superb Microvascular Imaging (SMI). Vid...
| Publicado en: | European Radiology Vol. 28; no. 3; pp. 1046 - 1054 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127990331&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127990331 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Mar2018 vid: 28 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 127990331 127990331 NLM29022101 127990331 10.1007/s00330-017-5016-4 NLM29022101 127990331 ppf: 1046 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Microflow imaging: New Doppler technology to detect low-grade inflammation in patients with arthritis. aug: au: Lim, A. K. P. Satchithananda, K. Dick, E. A. Abraham, S. Cosgrove, D. O. affil: Department of Imaging, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, W6 8RF, London, UK sug: subj: Arthritis, Rheumatoid Ultrasonography, Doppler Methods Synovitis Ultrasonography Methods Aged Blood Vessels Visual Analog Scaling Female Human Prospective Studies Image Interpretation, Computer Assisted Methods Joints Blood Supply Middle Age Male Adult Aged, 80 and Over Validation Studies Comparative Studies Evaluation Research Multicenter Studies Arthritis Impact Measurement Scales Impact of Events Scale Aged: 65+ years Middle Aged: 45-64 years Adult: 19-44 years Aged, 80 & over Female Male ab: Aim: To assess the efficacy of microvascular imaging in detecting low-grade inflammation in arthritis compared with Power Doppler ultrasound (PDUS).Method and Materials: Patients presenting for ultrasound with arthralgia were assessed with grey-scale, PDUS and Superb Microvascular Imaging (SMI). Videoclips were stored for analysis at a later date. Three musculoskeletal radiologists scored grey-scale changes, signal on PDUS and/or SMI within these joints. If a signal was detected on both PDUS and SMI, the readers graded the conspicuity of vascular signal from the two Doppler techniques using a visual analogue scale.Results: Eighty-three patients were recruited with 134 small joints assessed. Eighty-nine of these demonstrated vascular flow with both PD and SMI, whilst in five no flow was detected. In 40 joints, vascularity was detected with SMI but not with PDUS (p = 0.007). Out of the 89 joints with vascularity on both SMI and PDUS, 23 were rated as being equal; while SMI scored moderately or markedly better in 45 cases (p <0.001).Conclusion: SMI is a new Doppler technique that increases conspicuity of Doppler vascularity in symptomatic joints when compared to PDUS. This allows detection of low grade inflammation not visualised with Power Doppler in patients with arthritis.Key Points: • SMI detects vascularity with improved resolution and sensitivity compared to Power Doppler. • SMI can detect low-grade inflammation not seen with Power Doppler. • Earlier detection of active inflammation could have significant impact on treatment paradigms. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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