Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study.
Objectives: To evaluate differences in myocardial strain between pectus excavatum (PE) patients and healthy subjects (HS) assessed by cardiac MRI using the feature-tracking algorithm.Methods: Cardiac MRI was performed in 14 PE patients and 14 HS (9:5 male to female in each group; age 11-30 years) us...
| Publicado en: | European Radiology Vol. 28; no. 3; pp. 1276 - 1285 |
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| Autores principales: | , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127990342&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127990342 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Mar2018 vid: 28 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 127990342 127990342 NLM28894923 127990342 10.1007/s00330-017-5042-2 NLM28894923 127990342 ppf: 1276 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Differences in myocardial strain between pectus excavatum patients and healthy subjects assessed by cardiac MRI: a pilot study. aug: au: Lollert, André Emrich, Tilman Eichstädt, Jakob Kampmann, Christoph Abu-Tair, Tariq Turial, Salmai Düber, Christoph Kreitner, Karl-Friedrich Staatz, Gundula affil: Department of Diagnostic and Interventional Radiology, Section of Paediatric Radiology, Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany sug: subj: Funnel Chest Diagnosis Ventricular Dysfunction, Right Diagnosis Heart Ventricle Ventricular Function, Right Physiology Magnetic Resonance Imaging Methods Myocardium Pathology Ventricular Dysfunction, Right Etiology Young Adult Adult Funnel Chest Physiopathology Research Subjects Child Male Funnel Chest Complications Female Ventricular Dysfunction, Right Physiopathology Pilot Studies Adolescence Heart Ventricle Physiopathology Human Adult: 19-44 years Child: 6-12 years Adolescent: 13-18 years Male Female ab: Objectives: To evaluate differences in myocardial strain between pectus excavatum (PE) patients and healthy subjects (HS) assessed by cardiac MRI using the feature-tracking algorithm.Methods: Cardiac MRI was performed in 14 PE patients and 14 HS (9:5 male to female in each group; age 11-30 years) using a 3T scanner. Post-examination analysis included manual biventricular contouring with volumetry and ejection fraction measurement by two independent radiologists. Dedicated software was used for automated strain assessment.Results: In five of the PE patients, the right ventricular ejection fraction was slightly impaired (40-44 %). PE patients had a significantly higher left ventricular longitudinal strain (P=0.004), mid (P=0.035) and apical (P=0.001) circumferential strain as well as apical circumferential strain rate (P=0.001), mid right ventricular circumferential strain (P=0.008) and strain rate (P=0.035), and apical right ventricular circumferential strain (P=0.012) and strain rate (P=0.044) than HS. The right ventricular longitudinal strain and strain rate did not differ significantly between PE patients and HS.Conclusions: Myocardial strain differs significantly between PE patients and HS. Higher myocardial strain in the mid and apical ventricles of PE patients indicates a compensation mechanism to enhance ventricular output against basal sternal compression.Key Points: • The right ventricle is frequently affected by the pectus excavatum deformity. • Cardiac MRI revealed differences in myocardial strain in pectus excavatum patients. • Pectus excavatum patients exhibited higher strain in the mid/apical ventricles. • A compensation mechanism to enhance ventricular output against sternal compression is possible. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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