Cytotoxic and antimicrobial effects of biosynthesized ZnO nanoparticles using of Chelidonium majus extract.

The basic goal of this study was to synthesize zinc oxide nanoparticles using the Chelidonium majus extract and asses their cytotoxic and antimicrobial properties. The synthesized ZnO NPs were characterized by UV-Vis, Scanning Electron Microscopy (SEM) with EDS profile, Fourier Transform Infrared Sp...

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Publicado en:Biomedical Microdevices Vol. 20; no. 1; pp. 1 - 14
Autores principales: Dobrucka, Renata, Dlugaszewska, Jolanta, Kaczmarek, Mariusz
Formato: Journal Article
Publicado: Springer Nature Mar2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10544-017-0233-9
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        atl: Cytotoxic and antimicrobial effects of biosynthesized ZnO nanoparticles using of Chelidonium majus extract.
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        au:
          Dobrucka, Renata
          Dlugaszewska, Jolanta
          Kaczmarek, Mariusz
        affil: Department of Industrial Products Quality and Ecology, Faculty of Commodity Science, Poznan University of Economics, al. Niepodległości 10, 61-875, Poznan, Poland
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      ab: The basic goal of this study was to synthesize zinc oxide nanoparticles using the Chelidonium majus extract and asses their cytotoxic and antimicrobial properties. The synthesized ZnO NPs were characterized by UV-Vis, Scanning Electron Microscopy (SEM) with EDS profile, Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), Transmission Electron Microscopy (TEM) and Atomic Force Microscopy (AFM). The aforementioned methods confirmed that the size of synthesized ZnO nanoparticles was at the range of 10 nm. The antimicrobial activity of ZnO nanoparticles synthesized using the Ch. majus extract was tested against standard strains of bacteria (Staphylococcus aureus NCTC 4163, Pseudomonas aeruginosa NCTC 6749, Escherichia coli ATCC 25922), yeast (Candida albicans ATCC 10231), filamentous fungi (molds: Aspergillus niger ATCC 16404, dermatophytes: Trichophyton rubrum ATCC 28188), clinical strains of bacteria (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus) and yeast (Candida albicans). The study showed that zinc oxide nanoparticles were excellent antimicrobial agents. What is more, biologically synthesized ZnO nanoparticles demonstrate high efficiency in treatment of human nonsmall cell lung cancer A549.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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