The Potential Virulence Factors of Providencia stuartii: Motility, Adherence, and Invasion.
<italic>Providencia stuartii</italic> is the most common<italic> Providencia</italic> species capable of causing human infections. Currently<italic> P. stuartii</italic> is involved in high incidence of urinary tract infections in catheterized patients. The ability of bacteria to swarm on semisolid...
| Publicado en: | BioMed Research International Vol. 2018; pp. 1 - 9 |
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| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2/21/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128116455&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128116455 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2/21/2018 vid: 2018 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 128116455 128116455 128116455 10.1155/2018/3589135 128116455 ppf: 1 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The Potential Virulence Factors of Providencia stuartii: Motility, Adherence, and Invasion. aug: au: Kurmasheva, Naziia Vorobiev, Vyacheslav Sharipova, Margarita Efremova, Tatyana Mardanova, Ayslu affil: Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia sug: subj: Virulence Gram-Negative Bacteria Immunology Cell Line Killer Cells, Natural Pathology Epithelial Cells In Vitro Studies Bacterial Colonization Cell Movement Human Cell Culture Techniques Microscopy Methods ab: <italic>Providencia stuartii</italic> is the most common<italic> Providencia</italic> species capable of causing human infections. Currently<italic> P. stuartii</italic> is involved in high incidence of urinary tract infections in catheterized patients. The ability of bacteria to swarm on semisolid (viscous) surfaces and adhere to and invade host cells determines the specificity of the disease pathogenesis and its therapy. In the present study we demonstrated morphological changes of<italic> P. stuartii</italic> NK cells during migration on the viscous medium and discussed adhesive and invasive properties utilizing the HeLa-M cell line as a host model. To visualize the interaction of<italic> P. stuartii</italic> NK bacterial cells with eukaryotic cells<italic> in vitro</italic> scanning electron and confocal microscopy were performed. We found that bacteria<italic> P. stuartii</italic> NK are able to adhere to and invade HeLa-M epithelial cells and these properties depend on the age of bacterial culture. Also, to invade the host cells the infectious dose of the bacteria is essential. The microphotographs indicate that after incubation of bacterial<italic> P. stuartii</italic> NK cells together with epithelial cells the bacterial cells both were adhered onto and invaded into the host cells. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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