Gut microbiota functions: metabolism of nutrients and other food components.

The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As such, the gut microbiota is a key factor in s...

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Publicado en:European Journal of Nutrition Vol. 57; no. 1; pp. 1 - 25
Autores principales: Rowland, Ian, Gibson, Glenn, Heinken, Almut, Scott, Karen, Swann, Jonathan, Thiele, Ines, Tuohy, Kieran
Formato: pictorial review tables/charts Journal Article
Publicado: Springer Nature Feb2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2018
      vid: 57
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-017-1445-8
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        atl: Gut microbiota functions: metabolism of nutrients and other food components.
      aug:
        au:
          Rowland, Ian
          Gibson, Glenn
          Heinken, Almut
          Scott, Karen
          Swann, Jonathan
          Thiele, Ines
          Tuohy, Kieran
        affil: , Department of Food and Nutritional Sciences, University of Reading, Whiteknights, RG6 6AP, Reading, UK
      sug:
        subj:
          Gut Microbiota
          Nutrients
          Energy Metabolism
          Dietary Supplements
          Metabolic Networks and Pathways
          Dietary Carbohydrates
          Dietary Proteins
          Polyphenols
          Bile Acids and Salts
          Vitamins
          Metabolomics
      ab: The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As such, the gut microbiota is a key factor in shaping the biochemical profile of the diet and, therefore, its impact on host health and disease. The important role that the gut microbiota appears to play in human metabolism and health has stimulated research into the identification of specific microorganisms involved in different processes, and the elucidation of metabolic pathways, particularly those associated with metabolism of dietary components and some host-generated substances. In the first part of the review, we discuss the main gut microorganisms, particularly bacteria, and microbial pathways associated with the metabolism of dietary carbohydrates (to short chain fatty acids and gases), proteins, plant polyphenols, bile acids, and vitamins. The second part of the review focuses on the methodologies, existing and novel, that can be employed to explore gut microbial pathways of metabolism. These include mathematical models, omics techniques, isolated microbes, and enzyme assays.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
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      ougenre: Article
    language: English
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