Anticonvulsant and Toxicological Evaluation of Parafluorinated/Chlorinated Derivatives of 3-Hydroxy-3-ethyl-3-phenylpropionamide.

Although the anticonvulsant activity of 3-hydroxy-3-ethyl-3-phenylproionamide (HEPP) is well-known, its use is limited by the pharmacotoxicological profile. We herein tested its fluorinated and chlorinated derivatives (F-HEPP andCl-HEPP)with two seizure models, maximal electroshock seizures (MES), a...

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Publicado en:BioMed Research International Vol. 2016; pp. 1 - 11
Autores principales: Garrido-Acosta, Osvaldo, Meza-Toledo, Sergio E., Anguiano-Robledo, Liliana, Soriano-Ursúa, Marvin A., Correa-Basurto, José, Davood, Asghar, Chamorro-Cevallos, Germán
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 1/1/2016
Acceso en línea:Ver este registro en EBSCOhost