Assessment of Subtle Changes in Diabetes-Associated Arteriosclerosis using Photoplethysmographic Pulse Wave from Index Finger.
Distortions in macro- and microcirculation are principal contributors to diabetes-associated complications. This study aimed at investigating the validity of applying non-invasive photoplethysmographic (PPG) waveform parameters in detecting diabetes-induced subtitle changes in arterial stiffness. Be...
| Publicado en: | Journal of Medical Systems Vol. 42; no. 3 |
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| Autores principales: | , , |
| Formato: | equations & formulas research tables/charts tracings Journal Article |
| Publicado: |
Springer Nature
Mar2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128310797&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128310797 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01485598 4N0 jtl: Journal of Medical Systems issn: 01485598 maglogo: N pubinfo: dt: Mar2018 vid: 42 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 128310797 128310797 128310797 10.1007/s10916-018-0901-1 128310797 ppf: 0 ppct: 1 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Assessment of Subtle Changes in Diabetes-Associated Arteriosclerosis using Photoplethysmographic Pulse Wave from Index Finger. aug: au: Hsu, Po-Chun Wu, Hsien-Tsai Sun, Cheuk-Kwan affil: Department of Electrical Engineering, National Dong-Hwa University, 974, Hualien, Taiwan sug: subj: Diabetes Mellitus Taiwan Arteriosclerosis Taiwan Plethysmography Pulse Wave Velocity Human Middle Age Aged Female Male Data Analysis Software Hemodynamics Aged, 80 and Over Taiwan Funding Source Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: Distortions in macro- and microcirculation are principal contributors to diabetes-associated complications. This study aimed at investigating the validity of applying non-invasive photoplethysmographic (PPG) waveform parameters in detecting diabetes-induced subtitle changes in arterial stiffness. Between July 2009 and October 2010, totally 94 middle-aged and elderly subjects were recruited including 48 without diabetes (Group 1) and 46 with the disease (Group 2). Demographic (i.e., age, gender), anthropometric (body-mass index), biochemical (i.e., glycated hemoglobin concentration), and hemodynamic (i.e., systolic blood pressure, heart rate) parameters were obtained. Crest time (CT) and crest time ratio (CTR) computed from PPG signals acquired from left index finger were compared with left index finger pulse wave velocity (PWVfinger) obtained from six-channel ECG-PWV system to investigate the differences between the two groups and the associations of these indices with the parameters of testing subjects. Significant difference was only noted in CTR between the two groups (<italic>P</italic> < 0.005). Despite correlation of both CT and CTR with age, only CTR demonstrated significant associations with hemodynamic parameters. CTR could differentiate diabetic patients from healthy individuals despite absence of difference in arterial stiffness assessed by conventional PWV, highlighting its superior sensitivity to subtle changes in diabetes-associated arteriosclerosis. pubtype: Academic Journal doctype: equations & formulas research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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