Relationship between QRS measurements and left ventricular morphology and function in asymptomatic individuals.

Background and Aim: QRS amplitude and duration are associated with increased left ventricular (LV) volume, mass and dysfunction. However, the diagnostic concordance between QRS measurements and LV morphology and function, as shown by Doppler echocardiography, is not well established. We investigated...

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Publicado en:Echocardiography Vol. 35; no. 3; pp. 301 - 308
Autores principales: Vancheri, Federico, Vancheri, Sergio, Henein, Michael
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Mar2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2018
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.13782
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        atl: Relationship between QRS measurements and left ventricular morphology and function in asymptomatic individuals.
      aug:
        au:
          Vancheri, Federico
          Vancheri, Sergio
          Henein, Michael
        affil: Internal Medicine, Hospital S.Elia, Caltanissetta, Italy
      sug:
        subj:
          QRS Complex
          Ventricular Dysfunction, Left
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Echocardiography, Doppler
          Italy
          Descriptive Statistics
          Data Analysis Software
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background and Aim: QRS amplitude and duration are associated with increased left ventricular (LV) volume, mass and dysfunction. However, the diagnostic concordance between QRS measurements and LV morphology and function, as shown by Doppler echocardiography, is not well established. We investigated the relationships of QRS duration and amplitude with echocardiographic measurements of LV morphology and systolic and diastolic function in normal individuals. Methods: Individuals without signs or symptoms of coronary artery disease or heart failure, who underwent clinical examination as a part of a cross‐sectional survey for the prevalence of coronary risk factors, randomly selected from the population list in Caltanissetta, Italy, were included in the study. QRS duration and amplitude were automatically measured using inbuilt software. LV ejection and filling patterns were studied using Doppler echocardiography. Results: We studied 184 individuals (96 men and 88 women), mean age 55.9 (11.3). QRS duration increased by 5.4 ms for every 100 g increase in LV mass, and by 4.6 ms for each 10 mm increase in LV end‐diastolic diameter. The amplitude increased by 0.8 mm for every 100 g increase in LV mass. There was no relationship with LV dimensions. A nonlinear correlation was found between QRS amplitude and indexes of global dyssynchrony. The time‐voltage QRS area correlated with LV mass, dimensions and indexes of dyssynchrony. There was no relationship between QRS measurements and ejection fraction. Conclusions: QRS prolongation and increase in amplitude are strongly influenced by LV increased mass and volume, as well as by dyssynchrony, independently of ejection fraction.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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