Multifactorial non-cirrhotic hyperammonaemic encephalopathy.
A 51-year-old female presented with acute confusion associated with a non-specific headache and lethargy. The patient''s history included bipolar disorder on valproate and recent travel to northern Vietnam. The patient was subsequently found to have hyperammonaemia as well as a urinary tract infecti...
| Publicado en: | BMJ Case Reports Vol. 2018; pp. 1 - 4 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
BMJ Publishing Group
3/9/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128546487&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128546487 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1757790X B755 jtl: BMJ Case Reports issn: 1757790X maglogo: N pubinfo: dt: 3/9/2018 vid: 2018 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 128546487 10.1136/bcr-2017-223245 128546487 ppf: 1 ppct: 3 formats: tig: atl: Multifactorial non-cirrhotic hyperammonaemic encephalopathy. aug: au: Triplett, Katherine Elizabeth Murray, Ronan Anstey, Matthew affil: Intensive Care, Sir Charles Gairdner Hospital, Nedlands, Australia sug: ab: A 51-year-old female presented with acute confusion associated with a non-specific headache and lethargy. The patient''s history included bipolar disorder on valproate and recent travel to northern Vietnam. The patient was subsequently found to have hyperammonaemia as well as a urinary tract infection and bacteraemia with Klebsiellapneumoniae. The patient was presumed to have a multifactorial non-cirrhotic hyperammonaemic encephalopathy due to a combination of a urinary tract infection and bacteraemia with K. pneumoniae, a urease-producing bacteria, and also valproate use, a medication known to interfere with ammonia elimination. The patient's treatment included supportive care, ceasing valproate, empiric then rationalised antibiotics, N-acetylcysteine and L-carnitine. We present a case of non-cirrhotic hyperammonaemic encephalopathy and explain why it is multifactorial in origin. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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