Sagittal radiographic parameters demonstrate weak correlations with pretreatment patient-reported health-related quality of life measures in symptomatic de novo degenerative lumbar scoliosis: a European multicenter analysis.

OBJECTIVE Previous studies have demonstrated that among patients with adult spinal deformity (ASD), sagittal plane malalignment is poorly tolerated and correlates with suboptimal patient-reported health-related quality of life (HRQOL). These studies included a broad range of radiographic abnormaliti...

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Publicado en:Journal of Neurosurgery: Spine pp. 1 - 9
Autores principales: Faraj, Sayf S A, De Kleuver, Marinus, Vila-Casademunt, Alba, Holewijn, Roderick M, Obeid, Ibrahim, Acaroğlu, Emre, Alanay, Ahmet, Kleinstück, Frank, Pérez-Grueso, Francisco S, Pellisé, Ferran
Formato: research Journal Article
Publicado: American Association of Neurological Surgeons & the Journal of Neurosurgical Publishing Group Mar 23, 2018
Acceso en línea:Ver este registro en EBSCOhost
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        15475654
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      jtl: Journal of Neurosurgery: Spine
      issn: 15475654
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      dt: Mar 23, 2018
      pid: 13926
      pub: American Association of Neurological Surgeons & the Journal of Neurosurgical Publishing Group
      place: Rolling Meadows, Illinois
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        128645970
        128645970
        NLM29570046
        128645970
        10.3171/2017.8.SPINE161266
        NLM29570046
        128645970
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        atl: Sagittal radiographic parameters demonstrate weak correlations with pretreatment patient-reported health-related quality of life measures in symptomatic de novo degenerative lumbar scoliosis: a European multicenter analysis.
      aug:
        au:
          Faraj, Sayf S A
          De Kleuver, Marinus
          Vila-Casademunt, Alba
          Holewijn, Roderick M
          Obeid, Ibrahim
          Acaroğlu, Emre
          Alanay, Ahmet
          Kleinstück, Frank
          Pérez-Grueso, Francisco S
          Pellisé, Ferran
        affil: Department of Orthopedics, Radboud University Medical Center, Nijmegen, The Netherlands
      sug:
        subj:
          Quality of Life
          Scoliosis
          Scoliosis Psychosocial Factors
          Severity of Illness Indices
          Back Pain
          Aged, 80 and Over
          Europe
          Male
          Human
          Back Pain Etiology
          Spinal Diseases Psychosocial Factors
          Spinal Diseases
          Prospective Studies
          Self Report
          Back Pain Psychosocial Factors
          Female
          Middle Age
          Lumbar Vertebrae
          Retrospective Design
          Aged
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Scales
          Short Form-36 Health Survey (SF-36)
          Questionnaires
          Clinical Assessment Tools
          Aged, 80 & over
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: OBJECTIVE Previous studies have demonstrated that among patients with adult spinal deformity (ASD), sagittal plane malalignment is poorly tolerated and correlates with suboptimal patient-reported health-related quality of life (HRQOL). These studies included a broad range of radiographic abnormalities and various types of ASD. However, the clinical and radiographic characteristics of de novo degenerative lumbar scoliosis (DNDLS), a subtype of ASD, may influence previously reported correlation strengths. The aim of this study was to correlate sagittal radiographic parameters with pretreatment HRQOL in patients with symptomatic DNDLS. METHODS In this multicenter retrospective study of prospectively collected data, 74 patients with symptomatic DNDLS were enrolled based on anteroposterior and lateral 36-inch standing radiographs. Measurements included Cobb angle, coronal imbalance, pelvic incidence (PI), pelvic tilt (PT), lumbar lordosis (LL), sagittal vertical axis (SVA), thoracic kyphosis, pelvic incidence minus lumbar lordosis (PI-LL), T1-pelvic angle, and global tilt. HRQOL questionnaires included the Oswestry Disability Index (ODI), Scoliosis Research Society (SRS-22r), 36-item Short-Form Health Survey, and numeric rating scale (NRS) for back and leg pain. Correlations between radiographic parameters and HRQOL were assessed. Finally, HRQOL and increasing severity of sagittal modifiers (SVA, PI-LL, and PT) were evaluated. RESULTS Weak correlations were found between SVA and ODI (r = 0.296, p < 0.05) and PT with NRS back pain and the SRS pain domain (r = -0.260, p < 0.05, and r = 0.282, p < 0.05, respectively). Other sagittal radiographic parameters did not show any significant correlation with HRQOL. No significant differences in HRQOL were found concerning the increasing severity of PT, PI-LL, and SVA. CONCLUSIONS While DNDLS is a severe disabling condition, no noteworthy association between clinical and sagittal radiographic parameters was found through this study, demonstrating that sagittal radiographic parameters should not be considered the unique predictor of pretreatment suboptimal health status in this specific group of patients. Future studies addressing classification and treatment algorithms will have to take into account the existing subgroups of ASD.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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