Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn's Disease.

Background. We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 sign...

Full description

Bibliographic Details
Published in:BioMed Research International Vol. 2015; pp. 1 - 13
Main Authors: Shigetoshi Urabe, Hajime Isomoto, Tetsuya Ishida, Kazumi Maeda, Tatsuo Inamine, Shinji Kondo, Norihide Higuchi, Kayoko Sato, Ryohei Uehara, Hiroyuki Yajima, Haruhisa Machida, Chun Chuan Chen, Yasuhiro Fukuda, Fuminao Takeshima, Kazuhiko Nakao, Kazuhiro Tsukamoto
Format: algorithm pictorial research tables/charts Journal Article
Published: Wiley-Blackwell 10/19/2015
Online Access:View this record in EBSCOhost