Simulating Cardiac Electrophysiology Using Unstructured All-Hexahedra Spectral Elements.
We discuss the application of the spectral element method to the monodomain and bidomain equations describing propagation of cardiac action potential. Models of cardiac electrophysiology consist of a system of partial differential equations coupled with a system of ordinary differential equations re...
| Publicado en: | BioMed Research International Vol. 2015; pp. 1 - 16 |
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| Autores principales: | , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
10/25/2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128652174&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128652174 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 10/25/2015 vid: 2015 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 128652174 128652174 128652174 10.1155/2015/473279 128652174 ppf: 1 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Simulating Cardiac Electrophysiology Using Unstructured All-Hexahedra Spectral Elements. aug: au: Cuccuru, Gianmauro Fotia, Giorgio Maggio, Fabio Southern, James affil: CRS4, Loc. Pixina Manna, Edificio 1, 09010 Pula, Italy sug: subj: Electrophysiology Heart Physiology Computer Simulation Action Potentials Mathematics Human Cell Membrane Physiology Validity Models, Structural Benchmarking ab: We discuss the application of the spectral element method to the monodomain and bidomain equations describing propagation of cardiac action potential. Models of cardiac electrophysiology consist of a system of partial differential equations coupled with a system of ordinary differential equations representing cell membrane dynamics. The solution of these equations requires solving multiple length scales due to the ratio of advection to diffusion that varies among the different equations. High order approximation of spectral elements provides greater flexibility in resolving multiple length scales. Furthermore, spectral elements are extremely efficient to model propagation phenomena on complex shapes using fewer degrees of freedom than its finite element equivalent (for the same level of accuracy). We illustrate a fully unstructured all-hexahedra approach implementation of the method and we apply it to the solution of full 3D monodomain and bidomain test cases. We discuss some key elements of the proposed approach on some selected benchmarks and on an anatomically based whole heart human computational model. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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