Integrating Natural Language Processing and Machine Learning Algorithms to Categorize Oncologic Response in Radiology Reports.

A significant volume of medical data remains unstructured. Natural language processing (NLP) and machine learning (ML) techniques have shown to successfully extract insights from radiology reports. However, the codependent effects of NLP and ML in this context have not been wellstudied. Between Apri...

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Publicado en:Journal of Digital Imaging Vol. 31; no. 2; pp. 178 - 185
Autores principales: Po-Hao Chen, Zafar, Hanna, Galperin-Aizenberg, Maya, Cook, Tessa
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Integrating Natural Language Processing and Machine Learning Algorithms to Categorize Oncologic Response in Radiology Reports.
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          Po-Hao Chen
          Zafar, Hanna
          Galperin-Aizenberg, Maya
          Cook, Tessa
        affil: Department of Radiology, Perelman School of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
      sug:
        subj:
          Natural Language Processing
          Machine Learning
          Neoplasms Radiography
          Human
          Validity
          Medical Records
          Radiography, Abdominal
          Gynecologic Examination
          Tomography, X-Ray Computed
          Magnetic Resonance Imaging
          Neoplasms Diagnosis
          Disease Progression
          Logistic Regression
          Neural Networks (Computer)
      ab: A significant volume of medical data remains unstructured. Natural language processing (NLP) and machine learning (ML) techniques have shown to successfully extract insights from radiology reports. However, the codependent effects of NLP and ML in this context have not been wellstudied. Between April 1, 2015 and November 1, 2016, 9418 cross-sectional abdomen/pelvis CT and MR examinations containing our internal structured reporting element for cancer were separated into four categories: Progression, Stable Disease, Improvement, or No Cancer. We combined each of three NLP techniques with five ML algorithms to predict the assigned label using the unstructured report text and compared the performance of each combination. The three NLP algorithms included term frequency-inverse document frequency (TF-IDF), term frequency weighting (TF), and 16-bit feature hashing. The ML algorithms included logistic regression (LR), random decision forest (RDF), one-vs-all support vector machine (SVM), one-vs-all Bayes point machine (BPM), and fully connected neural network (NN). The best-performing NLP model consisted of tokenized unigrams and bigrams with TF-IDF. Increasing N-gram length yielded little to no added benefit for most ML algorithms. With all parameters optimized, SVMhad the best performance on the test dataset, with 90.6 average accuracy and F score of 0.813. The interplay between ML and NLP algorithms and their effect on interpretation accuracy is complex. The best accuracy is achieved when both algorithms are optimized concurrently.
      pubtype: Academic Journal
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    language: English
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